Ethical Standards and Regulatory Compliance in Preclinical Animal Studies : A Global Perspective

Tiwari, Prashant/ Kadiri, Sunil Kumar/ Kumar, Merugumolu Vijay

CABI Publishing（2026/07発売）

• 製本 Hardcover:ハードカバー版／ページ数 160 p.
• 言語 ENG
• 商品コード 9781836992110

Full Description

Animal studies play a vital role in the development of new medications, medical devices, and therapeutic methods. It is essential, however, that these studies adhere to ethical standards and international regulations to maintain scientific integrity and public confidence in biomedical research. Designed to provide researchers, regulatory professionals, ethics committee members, and institutional leaders with a thorough understanding of ethical standards and the challenges of compliance in preclinical animal research, this book covers regulatory frameworks from around the world, including the USA, European Union, Japan and Australia. Selected for their global impact, these regions represent diverse approaches to compliance while shaping standards internationally. This book also: - highlights the 3Rs principle of replacement, reduction and refinement within animal studies - includes case studies from prominent research institutions worldwide - provides practical advice on navigating international regulations Also exploring recent technological advancements that promote ethical research, including in vitro alternatives and computational models, this book encourages responsible and compliant research practices that promote scientific advancement while ensuring the humane treatment of laboratory animals.

Contents

1: Introduction to Ethical Standards in Preclinical Animal Research 2: Historical Perspectives on Animal Research Ethics 3: International Regulatory Frameworks for Preclinical Animal Studies 4: The 3Rs Principle: Replacement, Reduction, and Refinement 5: Animal Welfare and Ethical Compliance in Different Research Models 6: Institutional Animal Care and Use Committees (IACUC) and Ethical Review Boards 7: Designing Ethical and Compliant Animal Studies: Best Practices 8: Alternative Methods to Animal Use in Preclinical Research 9: Harmonizing Global Standards: Challenges and Opportunities 10: Risk Management and Ethical Decision-Making in Preclinical Studies 11: Pain Management, Euthanasia, and Humane Endpoints in Animal Studies 12: Training and Education for Ethical Animal Research 13: Case Studies in Ethical Compliance: Lessons from Leading Institutions 14: Legal Implications and Consequences of Non-Compliance 15: Future Directions in Ethical Standards for Preclinical Animal Studies