Full Description
Paratuberculosis, also referred to as Johne's disease, affects principally cattle, goats, sheep, buffalo, deer and other ruminants. It is common worldwide and responsible for significant economic losses in the ruminant livestock industries. A timely follow up to the first book on Paratuberculosis, this new edition is still the only comprehensive text providing both historical context and the latest developments in the field. Examining the epidemiology of paratuberculosis, the organism that causes the disease, and practical aspects of its diagnosis and control, it also addresses the link between paratuberculosis in the food chain and human health implications, including Crohn's disease. This new edition: · Builds on a strong foundation to update, streamline and better structure existing chapters with important new developments from the last decade, such as whole genome sequencing and phage-based assays; · Includes new chapters on the fast-growing field of whole genome based comparative genomics, and the increasing opportunities for disease control in low- and middle-income countries; · Increases inclusivity by bringing on board new rising star authors from diverse backgrounds to provide international perspectives. A truly comprehensive, critical reference resource, this book is an essential reference for large animal veterinarians, livestock industry personnel and those involved in the dairy and meat industries, as well as microbiologists, researchers and students in these fields.
Contents
1: Epidemiology, Global Prevalence and Economics of Infection 2: Mycobacterium avium subsp. paratuberculosis in Animal-derived Foods and the Environment 3: Paratuberculosis and Crohn's Disease 4: Genetics of Host Susceptibility to Paratuberculosis 5: Mycobacterium avium Complex 6: Comparative Genomics and Genomic Epidemiology of Mycobacterium avium subsp. Paratuberculosis Strains 7: Molecular Genetics of Mycobacterium avium subsp. paratuberculosis 8: Proteome and Antigens of Mycobacterium avium subsp. paratuberculosis 9: Host-Pathogen Interactions and Intracellular Survival of Mycobacterium avium subsp. paratuberculosis 10: Drug Susceptibility Testing & Antimicrobial Resistance in Mycobacterium avium subsp. Paratuberculosis 11: Paratuberculosis in Cattle 12: Paratuberculosis in Sheep 13: Paratuberculosis in Goats 14: Paratuberculosis in Deer, Camelids and Other Ruminants 15: Infection of Non-ruminant Wildlife by Mycobacterium avium subsp. paratuberculosis 16: Experimental Animal Models of Paratuberculosis 17: Immunology of Paratuberculosis Infection and Disease 18: Cultivation of Mycobacterium avium subsp. paratuberculosis 19: Diagnosis of Paratuberculosis by PCR 20: Immune-based Diagnosis of Paratuberculosis 21: Paratuberculosis Control Measures 22: Paratuberculosis Vaccines and Vaccination 23: Development of New Paratuberculosis Vaccines
