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Full Description
Capillary electrophoresis-mass spectrometry (CE-MS) has become a very useful analytical technique for the profiling of highly polar and charged metabolites in biological samples. In this book, the unique features of CE-MS for metabolomics studies are highlighted including CE separation modes, capillary coatings and practical aspects of CE-MS coupling alongside a comprehensive overview of recent technological developments and applications.
CE-MS can be considered a relatively new technique in the field of metabolomics and it is therefore important to inform the scientific community about the possibilities of advanced CE-MS approaches for metabolomics studies. This book outlines the potential of this technique for researchers working in metabolomics, bioanalytics and biomarker analysis.
Contents
Capillary Electrophoresis-Mass Spectrometry for Metabolomics - From Metabolite Analysis to Metabolic Profiling;
CE-MS Workflows for Metabolomics: A Focus on Sample Preparation;
Capillary Electrophoresis-Mass Spectrometry Using Non-covalently Coated Capillaries for Metabolic Profiling of Biological Samples;
Capillary Electrophoresis-Mass Spectrometry for Metabolomics Using New Interfacing Designs;
Stacking or On-line Sample Concentration in CE-MS for Metabolomics;
On-line Solid-phase Extraction Capillary Electrophoresis-Mass Spectrometry and Data Analysis Approaches for Metabolomics;
CE-MS for Anionic and Cationic Metabolic Profiling: System Optimization and Applications;
CE-MS for Metabolomics: A Comparison with Other Techniques;
Potential of CE-MS for Chiral Metabolic Profiling;
Single-cell Metabolomics with Capillary Electrophoresis-Mass Spectrometry;
Capillary Electrophoresis-Mass Spectrometry for Lipid Analysis;
Multisegment Injection-Capillary Electrophoresis-Mass Spectrometry: A Robust Platform for High Throughput Metabolite Profiling with Quality Assurance;
Subject Index
