化学生物学におけるＭＳ Mass Spectrometry in Chemical Biology : Evolving Applications

Peporine Lopes, Norberto (EDT)/ Roberto da Silva, Ricardo (EDT)

Royal Society of Chemistry（2017/11発売）

• 製本 Hardcover:ハードカバー版／ページ数 312 p.
• 言語 ENG
• 商品コード 9781782625278
• DDC分類 572

Full Description

Mass spectrometry is one of the most widespread technologies in chemistry and has been increasingly used in biology with the rise of omics sciences. This book summarizes some important methodological approaches in mass spectrometry and applications in the field of chemical biology.
The core chapters build on basic concepts introduced in the opening chapter and explore established fields such as high throughput screening, proteomics and metabolomics. Emerging applications of mass spectrometry in elucidating biosynthetic pathways, enzyme mechanisms and protein-protein interactions are then presented. Connections between these diverse research fields are highlighted throughout. The book concludes with a discussion of databases and future perspectives.
This book will be a useful tool to early chemical biology researchers wishing to incorporate mass spectrometry as a tool in their research.

Contents

Introduction;

Introduction to Mass Spectrometry Instrumentation and Methods Used in Chemical Biology;

Metabolomics;

Proteomics;

Mass Spectrometry for Discovering Natural Products;

Applications of Mass Spectrometry in Synthetic Biology;

Studying Enzyme Mechanisms Using Mass Spectrometry, Part 1: Introduction;

Studying Enzyme Mechanisms Using Mass Spectrometry, Part 2: Applications;

Chemical Biology Databases;

Perspectives for the Future