Full Description
This new volume delves into the extensive new research on inflammatory bowel disease (IBD) and gut microbiota that has led to effective therapeutic interventions. Highlighting novel methodologies and innovative treatment approaches, the book provides a comprehensive investigation of IBD, exploring the significance of gut microbiota and investigating the fundamental role of microbial imbalances in the initiation and progression of inflammatory processes as well as the prominent therapeutic consequences of restoring microbial homeostasis. From nanoparticle-based drug delivery systems that advance the bioavailability of the medicament to the use of bio-nanosensors for early detection of disease, the book covers a broad spectrum of inventions that hold potential for revolutionizing IBD treatment. The authors look at the impact of nutraceuticals, probiotics, prebiotics, functional foods, oral siRNA-based nanomedicine, and other novel drug delivery systems on gut microbiota for the management of IBD. The book also explores the role of reactive oxygen species (ROSs), superoxide dismutases (SODs), and inflammation in association with gut microbiota and IBD.
Contents
1. Introduction to Gut Microbiota and Inflammatory Bowel Disease: A Systematic Review 2. Pathogenesis of Gut Microbiota in Inflammatory Bowel Disease 3. Impact of Nutraceuticals on Gut Microbiota for the Management of Inflammatory Bowel Disease 4. Targeting Gut Microbiota with a Novel Drug Delivery System to Treat Inflammatory Bowel Disease 5. Management of Gut Microbiota-Derived Bacterial Metabolites Induced Inflammatory Bowel Disease 6. Correlation Between Host Genetics and Gut Microbiota in Inflammatory Bowel Disease 7. Oral siRNA-Based Nanomedicine for the Treatment of Inflammatory Bowel Disease 8. Site-Specific Targeted Novel Drug Delivery System for the Management of Inflammatory Bowel Disease 9. Surface-Modified Lipid Nanoparticle-Mediated Site-Specific Drug Delivery for Inflammatory Bowel Disease 10. Interplay Between Autophagy, Gut Microbiota, and Inflammatory Bowel Disease 11. Role of Reactive Oxygen Species, Superoxide Dismutases, and Inflammation in Association with Gut Microbiota and Inflammatory Bowel Disease 12. Composition of Gut Microbiota Dysbiosis and Functional Food to Treat Inflammatory Bowel Disease 13. Age-Related Gut Dysbiosis and Its Impact on Inflammatory Bowel Disease 14. Impact of Diseased Condition on Gut Microbiota in Inflammatory Bowel Disease 15. Role of Probiotics and Prebiotics in Inflammatory Bowel Disease 16. Application of Natural Products to Target Gut Microbiota for Inflammatory Bowel Disease Management 17. Future Prospects and Patents of Nanomedicines in Treating Inflammatory Bowel Disease