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Full Description
This new volume focuses on clinical biochemistry fundamentals, cell culture techniques, and drug discovery and development concepts. It deals with three different fields of clinical research: cell culture, clinical biochemistry, and drug discovery and development.
The book introduces cell animal and bacterial culture techniques and their potential uses as well as cell culture techniques. The biochemistry aspect of the book covers the principles of clinical biochemistry and biochemical analysis, biochemical aids to clinical diagnosis, measurement, and quality control. The book also presents important concepts in cell membrane receptor signal transduction pathways as drug targets.
The drug development focus of the book discusses the fundamentals of human disease and drug discovery. Various in silico, in vitro, and in vivo approaches for drug discovery are examined, along with a discussion on drug delivery carriers and clinical trials. Overall, the volume provides an overview of the journey from clinical fundamentals to clinical output.
Contents
1. An Introduction to Cell Culture 2. Animal Cell Culture 3. Bacterial Cell Culture 4. Potential Use of Cell Cultures 5. Principles of Clinical Biochemistry and Biochemical Analysis 6. Biochemical Aids to Clinical Diagnosis 7. Clinical Measurements and Quality Control 8. Cell Membrane Receptor 9. Mechanisms of Signal Transduction 10. Human Disease Drug Therapy and Drug Discovery 11. Drug Development: In Silico, In Vivo and System Biology Approach 12. Drug Development: Drug Delivery Carriers and Clinical Trial 13. Role of Micro RNA in Prostate Cancer Therapy 14. Pathogenesis, Molecular Mechanisms of Progression, and Therapeutic Targets of Liver Fibrosis: An Update 15. Prostate Cancer: Molecular Aspects, Biomarkers, and Chemo-Preventive Agents 16. Overview of Tuberculosis Biomarkers: An Update
