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Full Description
The last two decades of scientific research have progressed to the point where metabolic engineering, which involves the modifying of metabolic pathways of animals, plants, and bacterial cells at biochemical and molecular levels, is feasible. Conceptually, metabolic engineering takes into account the identification of major blocks or control points in a metabolic pathway at the molecular level followed by removal of these limitations with the help of various cellular engineering interventions. Understanding the metabolic pathways requires appropriate experiment setup, molecular biology and biochemistry methods, computational modelling, data analysis, and interpretation to allow the researchers to manipulate them as per their needs. This book comprises a total of 12 chapters from multiple contributors of different countries around the world, including Brazil, Egypt, India, Saudi Arabia, and Turkey. This book provides deep insight into the past, present, and future of metabolic engineering in the animal, microbial, and plant system, communicating interdisciplinary research and relevant results in biochemistry, molecular biology, applied microbiology, cellular physiology, cellular nutrition in health and disease, and biochemical engineering.
Contents
Foreword; Preface; Advances in Metabolic Engineering: Applications of CRISPR and Beyond; Significant Role of Metabolic Engineering in the Understanding of Cancer; Genome Editing in Metabolically Engineered Breast Cancer Cells with a Special Focus on Nano-Therapeutic Applications; Invertebrate and Vertebrate Cell Cultures in Bio-Therapeutics; An Insight in the Trends Timeline of Metabolic Engineering in Microbes and its Reflection on Future Scope; Metabolic Engineering Approach for Optimization of Microalgae Biorefinery using Phaeodactylum tricornutum as a Model Organism; Deciphering the Metabolic Adjustments of Engineered Plants using GC-MS: A Typical Workflow; Plants as a Bioreactor for Edible Vaccines: Emerging Excellence; Recent Developments and Future Prospects of Plant-Based Vaccines; Metabolic Engineering Approaches for Plant Secondary Metabolites Biosynthesis; Plant Metabolic Engineering: Promotion of Human Health; In Silico Studies Describing miRNAs and Their Regularity Processes in Industrial Important Medicinal and Aromatic Plants; Index.
