Full Description
Aneuploidy is an abnormal number of chromosomes, and is a type of chromosome abnormality. An extra or missing chromosome is a common cause of genetic disorders. Some cancer cells also have abnormal numbers of chromosomes. Aneuploidy occurs during cell division when the chromosomes do not separate properly between the two cells. Chromosome abnormalities occur in 1 of 160 live births. In this book, the authors present topical research in the study of the etiology, disorders and risk factors of aneuploidy, including the role of environmental pollutants as a mechanism of aneuploidy; ploidy in mitosis and meiosis; the spindle assembly checkpoint and aneuploidy; cohesions, genomic stability and cancer and aneuploidy in cultured human multipotent mesenchymal stromal cells.
Contents
Preface;AneuploidyPollutants;Ploidy in Mitosis and Meiosis: A Role of MAPK/Erk Network;The Spindle Assembly Checkpoint and Aneuploidy;The Role of Centromere Cohesion and Associated Proteins in Alzheimers Disease: A Relation to Aneuploidy?;Cohesins, Genomic Stability and Cancer;Adult Neurogenesis and Aneuploidy in Etiology, Pathogenesis and Pathology of Alzheimers Disease;Aneuploidy in Cultured Human Multipotent Mesenchymal Stromal Cells;Somatic and Germ Cells Spontaneous Aneuploidy Level in Healthy Fertile People;Sperm Aneuploidy and Male FertilityNER(01): GB IE
