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Full Description
Aging is a heterogeneous process with a progressive and general decrease of the organism functions that leads to a lower ability to adaptively react to changes and preserve homeostasis. Consequently, with ageing there is an increase in vulnerability to age-associated pathologies or simply the impairment of functions that leads to death. There are different rates of age-related physiological changes and the "biological age" determines the level of ageing experienced by each individual and therefore his/her life expectancy. This book discusses research which suggests that the functional parameters studied in neutrophils may be useful markers of "biological age" and predictors of longevity.
Contents
Introduction; The Aging Process, Longevity & Biological Age; Theories of Aging - The Integrated Theory of Aging; The Immune System as a Homeostatic System - The Psycho-Neuro-Endocrine-Immune Communication & Its Alteration with Aging; Immunosenescence & Age-Related Changes in the Innate Immunity; Functions of Neutrophils & Age-Related Changes; The Immune System -- A Marker of Biological Age & Predictor of Longevity; The Role of Oxidative Stress & Inflammatory Stress in Immunosenescence; The Role of the Phagocytic Cells in Oxi-Inflamm-Aging; Influential Factors Over the Functional & Redox Parameters in Neutrophils; Neutrophils & Their Roles in Disease; Strategies to Revitalize the Neutrophil Functions in Aging; Conclusion; Index.NER(01): GB IE
