Full Description
This volume brings together neuroscientists, psychiatrists,neurologists, and ethicists to discuss inter-related advances andchallenges emerging in the exciting field of brain stimulation.Discussion focuses on new methodologies that are aimed at bringingdirect measurement of brain activity to control electrical brainstimulation techniques. Such direct electrical stimulationtechniques offer a novel approach to precisely alter circuitmechanisms in the brain and a promise of temporal precision thatmay improve clinically relevant effects. A range of electricalstimulation techniques are discussed, with presentation of bothclinical research and animal models. Advancing brain stimulation asan investigative therapeutic technique and a science presentsseveral conceptual challenges, ethical question and pragmaticdifficulties inherent to the industrial academic collaborationsnecessary for research with medical devices. NOTE: Annals volumes are available for sale as individual booksor as a journal. For more information on institutional journalsubscriptions, please visit: http://ordering.onlinelibrary.wiley.com/subs.asp?ref=1749-6632&doi=10.111/(ISSN)1749-6632.ACADEMY MEMBERS: Please contact the New York Academy of Sciencesdirectly to place your order (www.nyas.org). Members of the NewYork Academy of Science receive full-text access to Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx formore information about becoming a member.
Contents
Brain stimulation in neurology and psychiatryevolving field vii Bruce Leuchter, Timothy A. Pedley, Sarah H. Lisanby, Helen S.Mayberg, and Nicholas D. Schiff
Deep brain stimulation for movement and other neurologicdisorders 1 Mahlon DeLong and Thomas Wichmann
What brain signals are suitable for feedback control of deepbrain stimulation in Parkinson s disease?9 Simon Little and Peter Brown
Transcranial magnetic stimulation on the modulation of gammaoscillations in schizophrenia 25 Faranak Farzan. Mera S. Barr, Yinming Sun, Paul B. Fitzgerald,and Zafiris J. Daskalakis
Increasing the validity of experimental models for depression36 Kafui Dzirasa and Herbert E. Covington, III
Toward a network model of dystonia 46 Claudia M. Hendrix and Jerrold L. Vitek
Moving toward a generalizable application of central thalamicdeep brain stimulation for support of forebrain arousal regulationin the severely injured brain 56 Nicholas D. Schiff
The ethics of research on deep brain stimulation fordepression: decisional capacity and therapeutic misconception69 Carl Erik Fisher, Laura B. Dunn, Paul P. Christopher, Paul E.Holtzheimer, Yan Leykin, Helen S. Mayberg, Sarah H. Lisanby, andPaul S Appelbaum
Challenges to deep brain stimulation: a pragmatic response toethical, fiscal, and regulatory concerns 80 Joseph J. Fins, Gary S. Dorfman, and Joseph J. Pancrazio
