Full Description
Recently, much attention has been focused on aging and obesity and the pivotal roles these conditions play in the development of chronic diseases such as diabetes, hypertension, and cancer. Several preclinical and clinical studies have revealed associations between aging and obesity and altered celluar environments--including genetic changes and inflammation-in the pathogenesis of many chronic disorders. Conventional methods for the treatment of cancer, including surgery, chemotherapy, and radiotherapy, result in limited success in certain cases and demonstrate additional modalities are required. In contrast to conventional treatments, some recent strategies are shifting to cancer prevention and treatment through physical exercise and better nutrition to control tumor progression, and to improve prognosis and rehabilitation in some cancer patients. This Annals volume presents a series of short reviews that focus on recent advances in, and future directions for, physical and nutritional bio-modulation and prevention of aging, obesity, and cancer, and suggest clinical care guidelines for the general population and for cancer patients and survivors who need proper physical exercise and optimal nutrition.
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Contents
Introduction to nutrition and physical activity in aging, obesity, and cancer / Young-Joon Surh et al Xenohormesis mechanisms underlying chemopreventive effects of some dietary phytochemicals / Young-Joon Surh
Dietary energy balance modulation of epithelial carcinogenesis: a role for IGF-1 receptor signaling and crosstalk / Tricia Moore, L. Allyson Checkley and John DiGiovanni
Tocotrienols: Inflammation and Cancer / Kalanithi Nesaretnam and Puvaneswari Meganathan
Neurogenic Contributions made by dietary regulation to hippocampal neurogenesis / Hee Ra Park and Jaewon Lee
Growth hormone-STAT5 regulation of growth, hepatocellular carcinoma, and liver metabolism / Myunggi Baik, Ji Hoon Yu and Lothar Hennighausen
Practical issues in genome-wide association studies for physical issues in genome-wide association studies for physical activity / Jaehee Kim et al
The growing challenge of obesity and cancer: an inflammatory issue / Alison E. Harvey, Laura M. Lashinger and Stephen D. Hursting
Metabolic approaches to overcoming chemoresistance in ovarian cancer / Dong Hoon Suh et al
Obesity-induced metabolic stresses in breast and colon cancer / Mi-Kyung Sung et al
Avian biomodels for use as pharmaceutical bioreactors and for studying human diseases / Gwonhwa Song and Jae Yong Han
Telomere dynamics: the influence of folate and DNA methylation / Carly J. Moores, Michael Fenech and Nathan J. O'Callaghan
Stem cell engineering : limitation, alternatives, and insight / Jeong Mook Lim, et al
Inhibitory mechanism of lycopene on cytokine expression in experimental pancreatitis / Hyeyoung Kim
Genomic biomarkers and clinical outcomes of physical activity / Alberto Izzotti
Impact of endurance and ultraendurance exercise on DNA damage / Karl-Heinz Wagner, Stefanie Reichhold and Oliver Neubauer
Myricetin is a potent chemopreventive phytochemical in skin carcinogenesis / Nam Joo Kang et al
Culinary plants and their potential impact on metabolic overload / Ji Yeon Kim and Oran Kwon
Inflammation-mediated obesity and insulin resistance as targets for nutraceuticals / Myung-Sunny Kim, Myeong Soo Lee and Dae Young Kown
Assessing estrogen signaling aberrations in breast cancer risk using genetically engineered mouse models / Priscilla A. Furth et al
The role of carbon monoxide in metabolic disease / Yeonsoo Joe et al
Combinatorial strategies employing nutraceuticals for cancer development / Yogeshwer Shukla and Jasmine George
Effects of physical activity on cancer prevention / Hye-Kyung Na and Sergiy Oliynyk
Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications / Young-Sam Keum
