Full Description
The mysteries of stress and its bodily effects revive old challenges and provide us with new ones. The Björntorp Symposium, which is recorded in this volume, focused on the role of stress and the brain in the pathologic conditions of obesity and metabolic syndrome, including in their physiology, pathophysiology, socioeconomic consequences, and therapeutic interventions. Special emphasis was placed on the metabolic consequences of stress, which might contribute to the alarming increase in the prevalence of obesity and its comorbidities in recent years.
The symposium and this volume are dedicated to the memory of a distinguished physician scientist, Professor Per Björntorp, whose pioneering ideas and research have set the foundations in this important field and continue to be a source of inspiration.
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Contents
Stress, Obesity and Metabolic Syndrome: Soul and Metabolism: C. Tsigos and G.P. Chrousos. Obesity and the Metabolic Syndrome: the Stress on Society: W.P.T. James, N. Rigby and R. Leach.
Part I: Stress through the Life Course:.
1. Fetal Origins of Stress-Related Adult Disease: E. Kajantie.
2. Birth-Weight, Stress in Childhood and the Metabolic Syndrome in Adult life: D. Phillips.
3. Metabolic Syndrome Manifestations in Classic Congenital Adrenal Hyperplasia:.
Do They Predispose to Atherosclerotic Cardiovascular Disease and Secondary Polycystic Ovary Syndrome?: E. Charmandari and G.P. Chrousos.
4. Stress in Women: Metabolic Syndrome and the PCOS: E. Diamanti-Kandarakis and F. Economou.
5. Stress, the Endoplasmic Reticulum and Insulin Resistance: P. Tsiotra and C. Tsigos.
Part II: Central Stress Activity and Peripheral Tissue Sensitivity in the Genesis of Obesity and the Metabolic Syndrome:.
6. Stress, Visceral Obesity and Metabolic Complications: I. Kyrou, G.P. Chrousos and C. Tsigos.
7. The Hypothalamic-Pituitary-Adrenal Axis Activity in Obesity and the Metabolic Syndrome: R. Pasquali, V. Vicennati, M. Cacciari and U.Pagotto.
8. Sympathetic system activity in obesity and the metabolic syndrome: N. Tendolouris, S. Liatis and N. Katsilambros.
9. A Brief Update of Glucocorticoid Receptor Variants and Obesity Risk: R. Rosmond, V. Radulovic and G. Holm.
10. Tissue Production of Cortisol by 11β-hydroxysteroid Dehydrogenase type 1 and Metabolic Risks: B.R. Walker and R. Andrew.
11. Peripheral Factors in the Metabolic Syndrome. The Pivotal Role of Adiponectin: C. Tsatsanis, V. Zacharioudaki, A. Androulidaki, E. Dermitzaki, I. Charalampopoulos, V. Minas, A. Gravanis and A. Margioris.
12. The Protective Role of Exercise on Stress System Dysregulation and Co-morbidities: A. Tsatsoulis.
13. Nutrition and Inflammatory Load: M.D. Kontogianni, A. Zambelas and C. Tsigos.
Part III: Targeting Components of the Stress System as Potential Therapies:.
14. Potential Uses of CRH Antagonists: A. Zoumakis and G. P. Chrousos.
15. Serotonin and Norepinephrine Reuptake Inhibition and Eating Behavior: V. Hainer, K. Kabrnova, B. Aldhoon, M. Kunesova, M. Wagenknecht.
16. Targeting the Cannabinoid System in Obesity and Metabolic Syndrome: C. Tsigos and I. Kyrou.
17. Targeting Components of the Stress System as Potential Therapies for the Metabolic Syndrome: The Peroxisome Proliferator Activated Receptors: V.D. Yumuk.
18. Regulation of Appetite and Insulin Action in Inflammatory States: K. Karalis.
19. Stress, Cytokines and Sleep Disorders: A. Vgontzas.
Index of Contributors
