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Full Description
The potent immune response of insects shares many of the characteristics of the mammalian acute phase response. This book discusses developments in the field of first line defence (antibody immunity). These developments focus on: the recognition of non-self; control of gene expression; and structures and activities of the induced molecules.
Contents
Molecular aspects of cell to cell communication in crustaceans; mudgut antibacterial defences of Manduca sexta following infection and during metamorphosis; cecropins and other antibacterial peptides - structures and mechanisms of action; defensins and protegrins - mammalian analogues of arthropod antimicrobial peptides; antibiotics from frogs, sharks, and man - novel mediators of a host defence; self, nonself, or no self?; on the usage of MHC class I molecules in immune recognition by natural killer cells and T cells; molecular and phylogenetic aspects of the complement system; invertebrate cytokines - principal mediators of host defences in invertebrates; KB-like motifs bind the cecropia and drosophila immunoresponsive factors and regulate the induction of the immune genes.
