Full Description
Editors Paul Cohen and Tyrrell Conway, who pioneered the use of metabolic mutants in competitive colonization assays, an approach now widely used to investigate the nutrition of pathogens in vivo, are uniquely qualified to advance our knowledge of this integrative field of research. They convened a group of contributors who are breaking new ground in understanding how bacterial metabolism is foundational to pathogenesis to share their expert perspectives and outlook for the future.
Contents
ContributorsPreface1 Glycolysis for the Microbiome Generation2 Pathogenesis - Thoughts from the Front Line3 Metabolic Adaptations of Intracellullar Bacterial Pathogens and their Mammalian Host Cells during Infection ("Pathometabolism")4 Small RNAs Regulate Primary and Secondary Metabolism in Gram-negative Bacteria 5 Sialic acid and N-acetylglucosamine Regulate type 1 Fimbriae Synthesis6 Trigger Enzymes: Coordination of Metabolism and Virulence Gene Expression7 Regulating the Intersection of Metabolism and Pathogenesis in Gram-positive Bacteria8 Borrelia burgdorferi: Carbon Metabolism and the Tick-Mammal Enzootic Cycle9 Metabolism and Pathogenicity of Pseudomonas aeruginosa Infections in the Lungs of Individuals with Cystic Fibrosis10 Metabolism and Fitness of Urinary Tract Pathogens11 Bacterial Metabolism in the Host Environment: Pathogen Growth and Nutrient Assimilation in the Mammalian Upper Respiratory Tract12 Saliva as the Sole Nutritional Source in the Development of Multispecies Communities in Dental Plaque13 Enteric Pathogens Exploit the Microbiota-generated Nutritional Environment of the Gut 14 The Roles of Inflammation, Nutrient Availability and the Commensal Microbiota in Enteric Pathogen Infection 15 Host Sialic Acids: A Delicacy for the Pathogen with Discerning Taste16 Commensal and Pathogenic Escherichia coli Metabolism in the Gut 343Index
