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Full Description
Molecular Genetics of Mycobacteria is a comprehensive collection of perspectives written by leading experts in the field. Molecular Genetics of Mycobacteria covers the key areas of current research in mycobacterial genetics, including genomics and genetic exchange, gene expression and regulation, proteomics, metabolism, biosynthesis, and drug sensitivities of M. tuberculosis, and presents genetic approaches for manipulating M. tuberculosis. This book is an invaluable resource for anyone interested in the molecular genetics and biology of mycobacteria.This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
GENOMES, GENOMICS, AND GENETIC EXCHANGE1. Gene Transfer in Mycobacterium tuberculosis: Shuttle Phasmids to Enlightenment, William R. Jacobs, Jr.2. Mycobacterial Pathogenomics and Evolution, Daria Bottai, Timothy P. Stinear, Philip Supply, and Roland Brosch3. BCG Vaccines, Vanessa Tran, Jun Liu, and Marcel A. Behr4. Distributive Conjugal Transfer: New Insights into Horizontal Gene Transfer and Genetic Exchange in Mycobacteria, Keith M. Derbyshire and Todd A. Gray5. Molecular Genetics of Mycobacteriophages, Graham F. Hatfull6. Genetics of Phage Lysis, Madalena PimentelGENE EXPRESSION AND REGULATION7. Sigma Factors: Key Molecules in Mycobacterium tuberculosis Physiology and Virulence, Riccardo Manganelli8. Transcription Factor Binding Site Mapping Using ChIP-Seq, Suma Jaini, Anna Lyubetskaya, Antonio Gomes, Matthew Peterson, Sang Tae Park, Sahadevan Raman, Gary Schoolnik, and James Galagan 9. Noncoding RNA in Mycobacteria, Kristine B. Arnvig, Teresa Cortes, and Douglas B. Young10.Two-Component Regulatory Systems of Mycobacteria, Tanya Parish11.Regulated Expression Systems for Mycobacteria and Their Applications, Dirk Schnappinger and Sabine EhrtTHE MYCOBACTERIAL PROTEOME12.Mycobacterium tuberculosis in the Proteomics Era, Martin Gengenbacher, Jeppe Mouritsen, Olga T. Schubert, Ruedi Aebersold, and Stefan H. E. Kaufmann13.Structural Annotation of the Mycobacterium tuberculosis Proteome, Nagasuma Chandra, Sandhya Sankaran, and Praveen Anand14.Cyclic AMP Signaling in Mycobacteria, Gwendowlyn S. Knapp and Kathleen A. McDonoughMETABOLISM15.The Physiology and Genetics of Oxidative Stress in Mycobacteria, Bridgette M. Cumming, Dirk Lamprecht, Ryan M. Wells, Vikram Saini, James H. Mazorodze, and Adrie J. C. Steyn16.Metabolomics of Central Carbon Metabolism in Mycobacterium tuberculosis, Anthony D. Baughn and Kyu Y. Rhee17.Mycobacterial Lipidomics, Emilie Layre, Reem Al-Mubarak, John T. Belisle, and D. Branch Moody18.Genetics of Mycobacterial Trehalose Metabolism, Rainer Kalscheuer and Hendrik Koliwer-Brandl19.Metallobiology of Tuberculosis, G. Marcela Rodriguez and Olivier Neyrolles20.Energetics of Respiration and Oxidative Phosphorylation in Mycobacteria, Gregory M. Cook, Kiel Hards, Catherine Vilcheze, Travis Hartman, and Michael Berney21.Molecular Basis of Drug Resistance in Mycobacterium tuberculosis, Keira A. Cohen, William R. Bishai, and Alexander S. Pym22.Resistance to Isoniazid and Ethionamide in Mycobacterium tuberculosis: Genes, Mutations, and Causalities, Catherine Vilcheze and William R. Jacobs, Jr.23.The Molecular Genetics of Fluoroquinolone Resistance in Mycobacterium tuberculosis, Claudine Mayer and Howard Takiff24.Mechanisms of Pyrazinamide Action and Resistance, Ying Zhang, Wanliang Shi, Wenhong Zhang, and Denis Mitchison25.Genetic Strategies for Identifying New Drug Targets, Andrej Trauner, Christopher M. Sassetti, and Eric J. Rubin26.Genetics of Peptidoglycan Biosynthesis, Martin S. Pavelka, Jr., Sebabrata Mahapatra, and Dean C. Crick27.Genetics of Mycobacterial Arabinogalactan and Lipoarabinomannan Assembly, Monika Jankute, Shipra Grover, Helen L. Birch, and Gurdyal S. Besra28.Genetics of Capsular Polysaccharides and Cell Envelope (Glyco)lipids, Mamadou Daffe, Dean C. Crick, and Mary Jackson29.The Molecular Genetics of Mycolic Acid Biosynthesis, Jakub Pawelczyk and Laurent Kremer30.Nucleotide Metabolism and DNA Replication, Digby F. Warner, Joanna C. Evans, and Valerie Mizrahi31.Double-Strand DNA Break Repair in Mycobacteria, Michael S. Glickman32.The Pup-Proteasome System of Mycobacteria, Nadine J. Bode and K. Heran Darwin33.Mycobacterium tuberculosis Serine/Threonine Protein Kinases, Sladjana Prisic and Robert N. HussonTHE MYCOBACTERIAL LIFESTYLE, PERSISTENCE, AND MACROPHAGE SURVIVAL34.The Spectrum of Drug Susceptibility in Mycobacteria, Bree B. Aldridge, Iris Keren, and Sarah M. Fortune35.The Sculpting of the Mycobacterium tuberculosis Genome by Host Cell-Derived Pressures, David G. Russell, Wonsik Lee, Shumin Tan, Neelima Sukumar, Maria Podinovskaia, Ruth J. Fahey, and Brian C. VanderVen 36.Evasion of Innate and Adaptive Immunity by Mycobacterium tuberculosis, Michael F. Goldberg, Neeraj K. Saini, and Steven A. Porcelli37.Mycobacterial Biofilms, Jacobs P. Richards and Anil K. Ojha
