基本説明
Covers the fundamental biology of A. fumigatus and discusses the wide range of clinical infection, plus the latest diagnostic and treatment strategies.
Full Description
Offers the latest insights into the fundamental biology and pathogenesis of A. fumigatus.Provides a combined synopsis of both A. fumigatus and its diseases and therapies.Encompasses the most up-to-date knowledge to serve as a resource guide for the next decade of study on this organism and the many diseases it causes.Covers the fundamental biology of A. fumigatus including specific features in genetics, biochemistry, and cell biology that can explain the virulence of this opportunistic pathogen.Discusses the wide range of clinical infection, plus the latest diagnostic and treatment strategies, in specific patient populations.This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
Table of ContentsIntroduction, David A. StevensI. The SpeciesMorphology and Reproductive Mode of Aspergillus fumigatus, Robert A. Samson, Janos Varga, and Paul S. Dyer Molecular Methods for Species Identification and Strain Typing of Aspergillus fumigatus, S. Arunmozhi Balajee and Corne H. W. Klaassen Aspergillus fumigatus Specificities as Deduced from Comparative Genomics, Amandine Gastebois, Karine Lambou, Joanne Wong Sak Hoi, and Fredj Tekaia Essential Genes in Aspergillus fumigatus, Wenqi Hu, Bo Jiang, and Terry RoemerII. Growth and Sensing, or Resisting Environmental StressAspects of Primary Carbon and Nitrogen Metabolism, Sven Krappmann Phospholipases of Aspergillus fumigatus, Geoffrey D. Robson Aspergillus fumigatus Secreted Proteases, Michel Monod, Olivier Jousson, and Utz Reichard Cations (Zn, Fe), Jose Antonio Calera and Hubertus Haas Conidial Germination in Aspergillus fumigatus, Nir Osherov Growth Polarity, Michelle Momany and Yainitza Hernandez-Rodriguez Biofilm Formation in Aspergillus fumigatus, Anne Beauvais and Frank-Michael Muller Signal Transduction, Gregory S. May and Taylor Schoberle Cell Wall of Aspergillus fumigatus: a Dynamic Structure, Isabelle Mouyna and Thierry Fontaine Genetic Regulation of Aspergillus Secondary Metabolites and Their Role in Fungal Pathogenesis, Robert A. Cramer, Jr., E. Keats Schwab, and Nancy P. Keller Aspergillus fumigatus: Survival and Death Under Stress, David S. Askew and Judith C. RhodesIII. Immune Defense Against AspergillusReactive Oxygen Intermediates, pH and Calcium, Elaine Bignell Innate Defense against Aspergillus: the Phagocyte, Michel Chignard Interactions of Aspergillus Infection and Allergy, Luigina Romani Dendritic Cells in Aspergillus Infection and Allergy, Luigina Romani CD4+ T-Cell Responses to Aspergillus fumitagus, Amariliz Rivera and Eric G. Pamer Innate Recognition of Aspergillus fumigatus by the Mammalian Immune System, Lisa M. Graham and Gordon D. BrownIV. The Spectrum of the DiseaseInvasive Pulmonary Aspergillosis, Aimee K. Zaas and Barbara D. Alexander Aspergillus Sinusitis and Cerebral Aspergillosis, Stefan Schwartz and Markus Ruhnke Chronic Aspergillosis, David W. Denning Allergic Bronchopulmonary Aspergillosis, Richard B. MossV. Diagnosis27. Histology and Radiology, Reginald Greene, Kazutoshi Shibuya, and Tsunihiro Ando28. Galactomannan and Anti-Aspergillus Antibody Detection for the Diagnosis of Invasive Aspergillosis, Paul E. Verweij29. Aspergillus PCR, P. Lewis White and Rosemary A. BarnesVI. Therapy30. Antifungal Polyenes, Andreas H. Groll and Thomas J. Walsh31. Azoles, Raoul Herbrecht and Yasmine Nivoix32. Echinocandins in the Treatment of Aspergillosis, Johan Maertens and Vincent Maertens33. Antifungal Drug Interactions, Russell E. Lewis34. Antifungal Mechanisms of Action and Resistance, David S. Perlin and Emilia Mellado35. Immunotherapy, Brahm H. Segal and Luigina R. RomaniVII. Timing of Antifungal Therapy36. Prophylaxis against Invasive Aspergillosis, Jo-Anne H. Young37. Therapy of Invasive Aspergillosis: Current Consensus and Controversies, Dimitrios P. Kontoyiannis and Kieren A. MarrVIII. Specific Patient Populations38. Invasive Aspergillosis in Solid Organ Transplant Recipients, Hsin-Yun Sun, Patricia Munoz, Emilio Bouza, and Nina Singh39. Invasive Aspergillosis in Malignancy and Stem Cell Transplant Recipients, Elio Castagnola and Claudio Viscoli40. Invasive Aspergillosis in Pediatric Patients, Emmanuel Roilides and Paraskevi PanagopoulouConclusion41. A Perspective View on Aspergillus fumigatus Research for the Next Ten Years, Jean-Paul Latge and William J. Steinbach
