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Full Description
An overview of the current understanding of how phagocytes recognize and respond to potentially pathogenic microbes.Provides a current understanding of the role of the phagocyte in host defense.Details the range of professional phagocyte cell lineages, including macrophages, PMNs, and dendritic cells.Outlines the functions of and challenges to the professional phagocyte.Improves our understanding of the cellular basis of antimicrobial responses.Integrates cell and molecular biology with immunological perspectives.This title is published by the American Society of Microbiology Press and distributed by Taylor and Francis in rest of world territories.
Contents
Table of ContentsForeword: What Would Darwin Have Said?Samuel C. SilversteinPart 1: Biology of the Professional Phagocyte1. Neutrophils ForeverTaco W. Kuijpers, Timo K. van den Berg, and Dirk Roos2. Macrophages: Microbial Recognition and ResponseAnnette Pluddemann and Siamon Gordon3. Dendritic Cells and Their Tissue Microenvironment during Exposure to PathogensA. Mortellaro, F. Granucci, M. Foti, and P. Ricciardi-CastagnoliPart 2: Membrane Receptors: Recognition, Adhesion, Phagocytosis, Chemotaxis, and Migration4. Fc Receptors and PhagocytosisSteven Greenberg and Benjamin M. Dale5. Chemokines and Phagocyte TraffickingTimothy J. Williams and Sara M. Rankin6. Toll-Like ReceptorsRicardo T. Gazzinelli, Kate Fitzgerald, and Douglas T. Golenbock7. C-Type Lectins: Multifaceted Receptors in Phagocyte BiologyAlessandra Cambi and Carl G. Figdor8. Integrins on PhagocytesWouter L. W. Hazenbos and Eric J. Brown9. Intracytosolic Sensing of Pathogens: Nucleic Acid Receptors, NLRs, and the Associated Responses during Infections and Autoinflammatory DiseasesThomas Henry and Denise M. Monack10. Phagocytes as a Source of the Fluid-Phase Pattern Recognition Receptor PTX3: Interplay between Cellular and Humoral Innate ImmunityAlberto Mantovani, Barbara Bottazzi, Andrea Doni, and Giovanni Salvatori11. Leukocyte ChemotaxisAnn Wheeler and Anne J. RidleyPart 3: Phagocytosis: Signaling, Cytoskeleton, and the Phagosome12. Signaling for PhagocytosisJoel A. Swanson13. Membrane Trafficking during Phagosome Formation and MaturationGregory D. Fairn, Elena Gershenzon, and Sergio Grinstein14. Acidification of Endosomes and PhagosomesSushmita Mukherjee and Frederick R. Maxfield15. Actin-Based Motility in Professional PhagocytesFrederick S. Southwick16. Functional Analysis of the Intraphagosomal Environment of the Macrophage: Fluorogenic Reporters and the Transcriptional Responses of Salmonella and MycobacteriumRobin M. Yates, Kyle H. Rohde, Robert B. Abramovitch, and David G. RussellPart 4: Bridging the Gap between the Innate and Acquired Immune Response17. Novel Anti-Inflammatory and Pro-Resolution Lipid Mediators in Induction and Modulation of Phagocyte FunctionCharles N. Serhan and Julio Aliberti18. Cytokines and Macrophages and Dendritic Cells: Key Modulators of Immune ResponsesFrank Kaiser and Anne O'Garra19. Macrophage Classical ActivationDonald C. Vinh and Steven M. Holland20. The Functional Heterogeneity of Activated MacrophagesXia Zhang and David M. Mosser21. Recognition and Removal of Apoptotic CellsPeter M. Henson and Donna L. Bratton22. Regulation and Antimicrobial Function of Inducible Nitric Oxide Synthase in PhagocytesChristian BogdanPart 5: Pathogens of the Professional Phagocyte23. The Multiple Interactions between Salmonella and PhagocytesJessica A. Thompson and David W. Holden24. Legionella, a Pathogen of Amoebae and MacrophagesMichele S. Swanson and Andrew Bryan25. The Role of Phagocytic Cells during Shigella Invasion of the Colonic MucosaGuy Tran Van Nhieu and Philippe Sansonetti26. Autophagy: a Fundamental Cytoplasmic Sanitation Process Operational in All Cell Types Including MacrophagesVojo Deretic27. Brucella, a Perfect Trojan Horse in PhagocytesSuzana P. Salcedo and Jean-Pierre Gorvel28. Interaction of Candida albicans with PhagocytesInes Faro-Trindade and Gordon D. Brown29. The Parasite Point of View: Insights and Questions on the Cell Biology of Trypanosoma and Leishmania Parasite-Phagocyte InteractionsKeith Gull30. Phagocyte Interactions with the Intracellular Protozoan Toxoplasma gondiiEric Y. Denkers31. Macrophages in Helminth Infection: Effectors, Regulators, and Wound HealersJudith E. Allen and Thomas A. WynnPart 6: Models of Host-Pathogen Interactions32. Dictyostelium discoideum: a Model Phagocyte and a Model for Host-Pathogen InteractionsZhiru Li and Ralph R. Isberg33. Phagocytosis in Drosophila melanogaster Immune ResponseVincent Leclerc, Jean-Marc Reichhart, Isabelle Caldelari, and Natalia Veresceaghina34. The Zebrafish as a Model of Host-Pathogen InteractionsJ. Muse Davis and Lalita Ramakrishnan35. Whole Genome Screens in MacrophagesBabak Javid and Eric J. Rubin
