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Full Description
This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others.
Written by world-renowned scientists in the field, Neural Stem Cells in Development, Adulthood and Disease presents cutting-edge studies of interest to both established neurogenesis researchers and readers with general interests in nervous system science. It is an authoritative addition to the Stem Cell Biology and Regenerative Medicine series.
Contents
1.Adult neurogenesis and regeneration: focus on non-mammalian vertebrates.- 2.Differential intrinsic and extrinsic regulations of the two adult neurogenic regions.- 3.The role of adult-born dentate granule neurons in the regulation of mood.- 4.Stem cells and neurogenesis in relation to dementia and Alzheimer's disease mouse models.- 5.Hippocampal neurogenesis in neurodegenerative movement disorders.- 6.Linking Adult Neurogenesis To Epilepsy Through Epigenetics.- 7.Activity-based maintenance of adult hippocampal neurogenesis: maintaining a potential for lifelong plasticity.- 8.Neural stem cells and demyelinating disease.- 9.Stem Cell-Based Therapies For Spinal Cord Regeneration.- 10.Direct reprogramming of somatic cells into induced neuronal cells: where we are and where we want to go.
