Full Description
Molecular Testing in Cancer provides a state of the art review of clinically relevant molecular pathology in cancer. The book provides a brief, easy to read review of commonly employed diagnostic molecular techniques including recently developed "next generation" analytic tools, and offers a system-based run-through of the utility of molecular testing in individual cancer types, as well as reviewing current markers in cancer diagnosis, prognosis, and management. The volume also provides a prospective for the future which includes recently characterized and emerging biomarkers.
Written by experts in the field, Molecular Testing in Cancer serves as a useful and comprehensive resource for pathologists, hematologists, laboratory technicians and molecular scientists.
Contents
Transitioning Diagnostic Molecular Pathology to the Genomic Era: Cancer Somatic Mutation Panel Testing.- Conventional and Molecular Cytogenetics in Cancer.- Comparative Genomic Hybridization and Array based CGH in Cancer.- Polymerase Chain Reaction.- Single Nucleotide Polymorphisms (SNPs).- Clinical Application of DNA Sequencing: Sanger and Next-Generation Platforms.- Microarray-based Investigations in Cancer.- Proteomics in Cancer Diagnostics.- Circulating Tumor Cells: A Non-Invasive Liquid Biopsy in Cancer.- Molecular Testing in Hematological Malignancies.- Molecular Testing in Breast Cancer.- Molecular Pathology of Gastrointestinal Tumors.- Molecular Testing in Pulmonary Tumors.- Molecular testing in Gynecological Malignancies.- Molecular Testing in Central Nervous System tumors.- Molecular Testing in Adult Kidney Tumors .- Molecular Testing in Prostate Cancer.- Molecular Testing in Urothelial Tumors.- Molecular Testing in Thyroid Cancer.- Molecular Testing of Head and Neck Tumors.- Molecular Testing in Bone and Soft Tissue Tumors.- Molecular testing in Cutaneous Melanoma.- Molecular Testing in Pediatric Tumors.- Pharmacogenomics in Molecular Oncology.- Quality Assurance in Molecular Testing of Cancer.
