Full Description
Students trained in traditional exercise physiology have learned the basic concepts of energy but often don't fully understand human energy consumption at the molecular level. Biochemistry Primer for Exercise Science, Fifth Edition, offers students a fundamental understanding of how biochemical processes underpin physical activity, performance, and overall health.
Reflecting the rapid development of the field, this foundational text continues to present the essentials of biochemistry-molecular biology, basic chemistry, metabolism, and transcription regulation-in an easy-to-understand format. With new and updated illustrations, the fifth edition features the most recent research in exercise biochemistry and contains new and expanded content on the following topics:
The structure, expression, interactions, and adaptations of proteins in the body (proteomics)
Muscle contraction and fatigue
The regulation of gene expression in health and disease
Control of biochemical and muscular adaptations to exercise and training through signaling pathways
The basics of signaling mechanisms associated with different types of exercise and adaptations to different forms of exercise training
New and developing research areas highlighted through Next Stage sidebars
Biochemistry Primer for Exercise Science, Fifth Edition, combines information from nutrition, physiology, and biochemistry to provide a clear explanation of metabolism and the human body's response to physical activity. Special elements throughout the text help to demystify this complex and dynamic field of study. Key points, sidebars, and chapter summaries help reinforce essential concepts. A comprehensive glossary and abbreviation and reference lists help students gain confidence in their understanding of exercise biochemistry.
With its combination of essential topics, new findings, and future directions in research, Biochemistry Primer for Exercise Science, Fifth Edition, provides a foundational understanding on the working of cellular and integrative whole-body metabolism and the human body's response to physical activity.
Contents
Tribute to Michael E. Houston
Part I. Proteins and Enzymes: The Basis of Biochemistry
Chapter 1. Amino Acids, Peptides, and Proteins
Nature of Amino Acids
Characteristics of Peptides
Structure of Proteins
Proteomics
Chapter Wrap-Up
Chapter 2. Enzymes
Enzymes as Catalysts
Rates of Enzymatic Reactions
Enzyme Cofactors
Classification of Enzymes
Oxidations and Reductions
Protein Transporters
Regulation of Enzyme Activity
Measurement of Enzyme Activity
Chapter Wrap-Up
Chapter 3. Gene Transcription and Protein Synthesis
DNA and RNA
Transcription
Posttranscriptional Modifications of RNA
Translation
Posttranslational Processing of Polypeptides
Protein Degradation
Regulation of Gene Expression in Exercise and Training
Chapter Wrap-Up
Part II. Metabolism: Regulation and Adaptation to Exercise and Training
Chapter 4. Energy Systems and Bioenergetics
Energy Requirements of Skeletal Muscle
Energy-Rich Phosphates
Energy Systems
Bioenergetics
Chapter Wrap-Up
Chapter 5. Oxidative Phosphorylation
Overview of Metabolism
Mitochondria
Citric Acid Cycle
Electron Transport Chain
Coupled Phosphorylation
Regulation of Oxidative Phosphorylation
Quantification of Redox Reactions
Oxidants and Antioxidants
Chapter Wrap-Up
Chapter 6. Carbohydrate and Related Metabolism
Carbohydrates
Cellular Uptake of Glucose
Phosphorylation of Glucose
Glycolysis
Glycogen Metabolism
Lactate Metabolism
Oxidation of Cytoplasmic NADH
Gluconeogenesis
Pentose Phosphate Pathway
Signaling Pathways
Carbohydrate, Exercise Performance, and Fatigue
Chapter Wrap-Up
Chapter 7. Lipid Metabolism
Types of Lipids
Fat Storage and Metabolism
Oxidation of Fatty Acids
Oxidation of Ketone Bodies
Synthesis of Fatty Acids
Fat as Fuel for Exercise
Metabolism During Exercise: Fat Versus Carbohydrate
Adipose Tissue as an Endocrine Tissue
Cholesterol
Chapter Wrap-Up
Chapter 8. Amino Acid and Protein Metabolism
Overview of Amino Acid Metabolism
Degradation of Amino Acids
Urea Cycle
Fate of Amino Acid Carbon Skeletons
Amino Acid Metabolism During Exercise
Additional Roles for Amino Acids
Dietary Protein, Amino Acids, and Muscle Mass
Chapter Wrap-Up
Appendix. Answers to Review Questions
