Full Description
In this timely volume, eminent researchers provide detailed coverage of the relevant function of neurochemical correlates to cerebral ischemia as well as their pathophysiological significance.
Contents
1 Introduction: Current Biochemical and Molecular Approaches to the Study of Cerebral Ischemia.- 2 Metabolic Correlates of Focal Ischemia.- 3 Role of Pyruvate Dehydrogenase in Ischemic Injury.- 4 Disturbances of Protein and Polyamine Metabolism after Reversible Cerebral Ischemia.- 5 Oxygen Dependence of Neuronal Metabolism.- 6 Dysmetabolism in Lipid Brain Ischemia.- 7 Involvement of Calcium, Lipolytic Enzymes, and free Fatty acids in Ischemic Brain Trauma.- 8 Arachidonic Acid Lipoxygenase Products Participate in the Pathogenesis of Delayed Cerebral Ischemia.- 9 Biochemical Changes and Secondary Tissue Injury after Brain and Spinal Cord Ischemia!Reperfusion.- 10 Free Fatty Acid Liberation in the Pathogenesis and Therapy of Ischemic Brain Damage.- 11 Cerebral Ischemia and Polyphosphoinositide Metabolism.- 12 Protection Against Ischemic Brain Damage by Excitatory Amino Acid Antagonists.- 13 Acute Alterations in Phosphoinosttide Turnover.- 14 New Insights into the Role of Oxygen Radicals in Cerebral Ischemia.- 15 Biochemical Factors and Mechanisms of Secondary Brain Damage in Cerebral Ischemia and Trauma.- 16 Modulators of Neural Cell Signaling and Triggering of Gene Expression Following Cerebral Ischemia.- 17 Cellular and Metabolic Significance of Cellular Acid-Base Shifts in Human Stroke.