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Full Description
The Second International Workshop on Human Leukocyte Differentia- tion Antigens was held in Boston, September 17-20, 1984. More than 350 people interested in leukocyte differentiation agreed to exchange reagents and participate in this joint venture. All in all, in excess of 400 antibodies directed against surface structures on T lymphocytes, B lymphocytes, and myeloid-hematopoietic stem cells were characterized. Because of the enormous quantity of serologic, biochemical, and functional data, Leuko- cyte Typing II has been divided into three volumes. These books represent the written results of workshop participants. They should be helpful to both researchers and clinicians involved in scientific endeavors dealing with these broad fields of immunobiology. To those who delve into the various sections of the volumes', it will become evident that the work speaks for itself. I am deeply indebted to the section editors, Barton F. Haynes, Volume 1, Human T Lymphocytes, Lee M. Nadler, Volume 2, Human B Lympho- cytes, and Irwin D.
Bernstein, Volume 3, Human Myeloid and Hemato- poietic Cells for their major contributions in planning, executing, and summarizing the workshop, as well as council members John Hansen, Laurence Boumsell, Walter Knapp, Andrew McMichael, Alain Bernard, Cesar Milstein, and Stuart F. Schlossman. I would also like to thank the National Institutes of Health, World Health Organization, and Interna- tional Union ofImmunological Societies for making this meeting possible.
Contents
1. Joint Report of the Myeloid Section of the Second International Workshop on Human Leukocyte Differentiation Antigens.- 2. Serological, Biochemical, and Cytogenetic Studies with the Granulocyte Monoclonal Antibodies of the "M Protocol".- 3. Glycolipid Specificities of Anti-Hematopoietic Cell Antibodies.- 4. Antibodies Specific for the Mac-1, LFA-1, p150,95 Glycoproteins or Their Family, or for Other Granulocyte Proteins, in the 2nd International Workshop on Human Leukocyte Differentiation Antigens.- 5. Functional Studies with Monoclonal Antibodies Against Function-Associated Leukocyte Antigens.- 6. Phosphorylation of a, ß Subunits of 180/100-Kd Polypeptides (LFA-1) and Related Antigens.- 7. Serological, Immunochemical, and Functional Analysis of the Heterogeneity of the Workshop Monoclonal Antibodies Recognizing the LFA-1 Antigen.- 8. Monoclonal Antibodies That Identify Mo1 and LFA-1, Two Human Leukocyte Membrane Glycoproteins: A Review.- 9. Localization of the Human NA1 Alloantigen on Neutrophil Fc-?-Receptors.- 10. Murine Monoclonal Anti-P.- 11. NK-Associated and LFA-1 Antigens: Phenotypic and Functional Studies Utilizing Human NK Clones.- 12. Reactivity Patterns of Monoclonal Antibodies Against Myeloid-Associated Antigens with Human Natural Killer Cells.- 13. A Map of the Cell Surface Antigens Expressed on Resting and Activated Human Natural Killer Cells.- 14. Inhibition of CFU-GM, BFU-E, and CFU-GEMM Colony Formation by Monoclonal Antibodies Selected from the Myeloid Panel.- 15. Reactivity of Anti-Myeloid Monoclonal Antibodies with Committed Hematopoietic Precursor Cells.- 16. Study of the Antigenic Profile of Normal Myelo-Monocytic Progenitors and Leukemic Cell Lines Using Monoclonal Antibodies.- 17. Expression of Antigens Present on HematopoieticProgenitor Cells by Cells of Certain Hematopoietic Lineages.- 18. Heterogeneous Expression of Myelo-Monocytic Markers on Selected Non-Lymphoid Cells.- 19. Immunohistochemical Reactivity of Anti-Myeloid/Stem Cell Workshop Monoclonal Antibodies in Thymus, Lymph Node, Lung, Liver, and Normal Skin.- 20. Immunohistological Studies of Anti-Myeloid Monoclonal Antibodies.- 21. Immunohistological Characterization of Myeloid and Leukemia-Associated Monoclonal Antibodies.- 22. Differentiation-Associated Stages of Clonogenic Cells in Acute Myeloblastic Leukemia Identified by Monoclonal Antibodies.- 23. Antigenic Analysis of Human Malignant Myeloid Cells by Immunoperoxidase.- 24. Expression of Lymphocyte Antigens on Blast Cells from Patients with Chronic Granulocytic Leukemia.- 25. Frequent Detection of Erythroid and Platelet Antigens in Myeloid Blast Crisis of CML.- 26. Reactivity of a Monoclonal Antibody Defining Human Hematopoietic Multipotential Progenitors.- 27. Expression of an Acute Myelogenous Leukemia-Associated Antigen (NHL-30.5) on Immature Leukemic Cells.- 28. Down-Regulation of Promyelocytic Cell Transferrin Receptor Expression by Cholera Toxin and Cyclic Adenosine Monophosphate.- 29. Expression of Myeloid and B Cell-Associated Antigens on T Lineage Cells.- 30. Different Stages of T Cell Differentiation and Microenvironments in the Thymus as Defined by Immunohistology.
