Full Description
Diagnostic Pathology of the Intestinal Mucosa - An Atlas and Review of Biopsy Interpretation offers a comprehensive overview of intestinal mucosal structure as defined through peroral or endoscopic biopsy specimens obtained in normal and disease states. It describes small intestinal biopsy pathology in conjunction with morphologic, functional, and pathophysiologic correlations. Routine methods of processing tissues for light microscopy, electron microscopy, histochemistry, and light- and electron- microscopic-immunoperoxidase techniques are presented so that the novice in the area of intestinal structure may have an easily accessible reference for setting up a morphologic laboratory.
Contents
1 Processing of Biopsy Specimens for Light and Electron Microscopy.- Sampling.- Orienting the Sample.- Processing Specimens for Light Microscopy.- Processing Specimens for Electron Microscopy.- 2 Biopsy Interpretation—Light Microscopy.- Normal Villous Architecture.- Normal Epithelium.- Normal Lamina Propria.- Normal Muscularis Mucosae.- 3 Biopsy Interpretation—Electron Microscopy.- Intestinal Epithelial Cells.- Intraepithelial Lymphocytes and Immune Cells of the Lamina Propria.- Other Cells of the Lamina Propria.- Metaplasia.- 4 Immunoperoxidase Techniques: Light and Electron Microscopy Applications.- Materials and Methods: Light Microscopy.- Materials and Methods: Electron Microscopy.- 5 The Abnormal Biopsy.- Recognizing Artifacts.- Interpreting the Abnormal Biopsy.
