Full Description
Since 1927, Goldman-Cecil Medicine has been the world's most influential internal medicine resource. In the ground-breaking 25th edition, your original purchase ensures you will be up-to-date without the need for a subscription. Through the new, more powerful Expert Consult eBook platform, this "living text" provides continuous updates that will integrate the latest research, guidelines, and treatments into each chapter, ensuring that the content is as current as the day this edition was first published. Goldman-Cecil Medicine offers definitive, unbiased guidance on the evaluation and management of every medical condition, presented by a veritable "Who's Who" of modern medicine. A practical, straightforward style; templated organization; evidence-based references; and robust interactive content combine to make this dynamic resource quite simply the fastest and best place to find all of the authoritative, state-of-the-art clinical answers you need."The content is superb, authoritative and not surprisingly very up to date." Reviewed by: Dr Harry Brown, on behalf of Glycosmedia Date: July 2015 Expert Consult eBook version included with print purchase:Access continuous updates from Editor Lee Goldman, MD, who thoroughly reviews internal medicine and specialty journals, updating online content to reflect the latest guidelines and translating that evidence into treatment. Interactive Q&A section features over 1,500 board-style questions and answers to aid in preparing for certification or recertification exams.Outstanding supplementary tools include figures, tables, videos, heart and lung sounds, treatment and management algorithms, fully integrated references, and thousands of illustrations and full-color photos.Search all of the text, figures, supplementary material, and references from the book on a variety of devices and at no additional cost - Expert Consult access is included with this title!Practical, bulleted, highly templated text with easy-to-use features including flow charts and treatment boxes.New chapters on global health, cancer biology and genetics, and the human microbiome in health and disease keep you on the cutting edge of medicine.Today's most current evidence-based medicine guidelines help you form a definitive diagnosis and create the best treatment plans possible.Focused coverage of the latest developments in biology includes the specifics of current diagnosis, therapy, and medication doses.The reference of choice for every stage of your career! Goldman-Cecil Medicine is an ideal learning tool for residents, physicians, and students as well as a valuable go-to resource for experienced healthcare professionals. Cecil - the best internal medicine resource available since 1927 - far exceeds the competition in versatility, ease-of-use and up-to-datedness.
Contents
VOLUME I1 Approach to Medicine, the Patient, and the Medical Profession: Medicine as a Learned and Humane Profession2 Bioethics in the Practice of Medicine3 Care of Dying Patients and Their Families4 Cultural Context of Medicine5 Socioeconomic Issues in Medicine6 Global Health7 Approach to the Patient: History and Physical Examination8 Approach to the Patient with Abnormal Vital Signs9 Statistical Interpretation of Data10 Using Data for Clinical Decisions11 Measuring Health and Health Care12 Quality of Care and Patient Safety13 Comprehensive Chronic Disease ManagementSECTION III: PREVENTIVE AND ENVIRONMENTAL ISSUES14 Counseling for Behavior Change15 The Periodic Health Examination16 Physical Activity17 Adolescent Medicine18 Immunization19 Principles of Occupational and Environmental Medicine20 Radiation Injury21 Bioterrorism22 Chronic Poisoning: Trace Metals and OthersSECTION IV: AGING AND GERIATRIC MEDICINE23 Epidemiology of Aging: Implications of an Aging Society24 Geriatric Assessment25 Common Clinical Sequelae of Aging26 Incontinence27 Neuropsychiatric Aspects of Aging28 Delirium or Acute Mental Status Change in the Older PatientSECTION V: CLINICAL PHARMACOLOGY29 Principles of Drug Therapy30 Pain31 Biology of Addiction32 Nicotine and Tobacco33 Alcohol Use Disorders34 Drugs of Abuse35 Immunosuppressing Drugs Including Corticosteroids36 Biologic Agents and Signaling Inhibitors37 Prostanoids, Aspirin, and Related Compounds38 Antithrombotic Therapy39 Complementary and Alternative MedicineSECTION VI: GENETICS40 Principles of Genetics41 Gene, Genomic, and Chromosomal Disorders42 The Inherited Basis of Common Diseases43 Application of Molecular Technologies to Clinical Medicine44 Regenerative Medicine, Cell, and Gene Therapies45 The Innate Immune System46 The Adaptive Immune System47 Mechanisms of Immune-Mediated Tissue Injury48 Mechanisms of Inflammation and Tissue Repair49 Transplantation Immunology50 Complement System in DiseaseSECTION VIII: CARDIOVASCULAR DISEASE51 Approach to the Patient with Possible Cardiovascular Disease52 Epidemiology of Cardiovascular Disease53 Cardiac Function and Circulatory Control54 Electrocardiography55 Echocardiography56 Noninvasive Cardiac Imaging57 Catheterization and Angiography58 Heart Failure: Pathophysiology and Diagnosis59 Heart Failure: Management and Prognosis60 Diseases of the Myocardium and Endocardium61 Principles of Electrophysiology62 Approach to the Patient with Suspected Arrhythmia63 Approach to Cardiac Arrest and Life-Threatening Arrhythmias64 Cardiac Arrhythmias with Supraventricular Origin65 Ventricular Arrhythmias66 Electrophysiologic Interventional Procedures and Surgery67 Arterial Hypertension68 Pulmonary Hypertension69 Congenital Heart Disease in Adults70 Atherosclerosis, Thrombosis, and Vascular Biology71 Angina Pectoris and Stable Ischemic Heart Disease72 Acute Coronary Syndrome: Unstable Angina and Non-ST Elevation Myocardial Infarction73 ST Segment Elevation Acute Myocardial Infarction and Complications of Myocardial Infarction74 Interventional and Surgical Treatment of Coronary Artery Disease75 Valvular Heart Disease76 Infective Endocarditis77 Pericardial Diseases78 Diseases of the Aorta79 Atherosclerotic Peripheral Arterial Disease80 Other Peripheral Arterial Diseases81 Peripheral Venous Disease82 Cardiac TransplantationSECTION IX: RESPIRATORY DISEASES83 Approach to the Patient with Respiratory Disease84 Imaging in Pulmonary Disease85 Respiratory Function: Mechanisms and Testing86 Disorders of Ventilatory Control87 Asthma88 Chronic Obstructive Pulmonary Disease89 Cystic Fibrosis90 Bronchiectasis, Atelectasis, Cysts, and Localized Lung Disorders91 Alveolar Filling Disorders92 Interstitial Lung Disease93 Occupational Lung Disease94 Physical and Chemical Injuries of the Lung95 Sarcoidosis96 Acute Bronchitis and Tracheitis97 Overview of Pneumonia98 Pulmonary Embolism99 Diseases of the Diaphragm, Chest Wall, Pleura, and Mediastinum100 Obstructive Sleep Apnea101 Interventional and Surgical Approaches to Lung DiseaseSECTION X: CRITICAL CARE MEDICINE102 Approach to the Patient in a Critical Care Setting103 Respiratory Monitoring in Critical Care104 Acute Respiratory Failure105 Mechanical Ventilation106 Approach to the Patient with Shock107 Cardiogenic Shock108 Shock Syndromes Related to Sepsis109 Disorders Due to Heat and Cold110 Acute Poisoning111 Medical Aspects of Injuries and Burns112 Envenomation113 RhabdomyolysisSECTION XI: RENAL AND GENITOURINARY DISEASES114 Approach to the Patient with Renal Disease115 Structure and Function of the Kidneys116 Disorders of Sodium and Water Homeostasis117 Potassium Disorders118 Acid-Base Disorders119 Disorders of Magnesium and Phosphorus120 Acute Kidney Injury121 Glomerular Disorders and Nephrotic Syndromes122 Tubulointerstitial Nephritis123 Obstructive Uropathy124 Diabetes and the Kidney125 Vascular Disorders of the Kidney126 Nephrolithiasis127 Cystic Kidney Diseases128 Hereditary Nephropathies and Developmental Abnormalities of the Urinary Tract129 Benign Prostatic Hyperplasia and Prostatitis130 Chronic Kidney Disease131 Treatment of Irreversible Renal FailureSECTION XII: GASTROINTESTINAL DISEASES132 Approach to the Patient with Gastrointestinal Disease133 Diagnostic Imaging Procedures in Gastroenterology134 Gastrointestinal Endoscopy135 Gastrointestinal Hemorrhage136 Disorders of Gastrointestinal Motility137 Functional Gastrointestinal Disorders: Irritable Bowel Syndrome, Dyspepsia, Chest Pain of Presumed Esophageal Origin, and Heartburn138 Diseases of the Esophagus139 Acid Peptic Disease140 Approach to the Patient with Diarrhea and Malabsorption141 Inflammatory Bowel Disease142 Inflammatory and Anatomic Diseases of the Intestine, Peritoneum, Mesentery, and Omentum143 Vascular Diseases of the Gastrointestinal Tract144 Pancreatitis145 Diseases of the Rectum and Anus146 Approach to the Patient with Liver Disease147 Approach to the Patient with Jaundice or Abnormal Liver Tests148 Acute Viral Hepatitis149 Chronic Viral and Autoimmune Hepatitis150 Toxin- and Drug-Induced Liver Disease151 Bacterial, Parasitic, Fungal, and Granulomatous Liver Diseases152 Alcoholic and Nonalcoholic Steatohepatitis153 Cirrhosis and Its Sequelae154 Hepatic Failure and Liver Transplantation155 Diseases of the Gallbladder and Bile DuctsSECTION XIV: HEMATOLOGIC DISEASES156 Hematopoiesis and Hematopoietic Growth Factors157 The Peripheral Blood Smear158 Approach to the Anemias159 Microcytic and Hypochromic Anemias160 Autoimmune and Intravascular Hemolytic Anemias161 Hemolytic Anemias: Red Blood Cell Membrane and Metabolic Defects162 The Thalassemias163 Sickle Cell Disease and Other Hemoglobinopathies164 Megaloblastic Anemias165 Aplastic Anemia and Related Bone Marrow Failure States166 Polycythemia Vera, Essential Thrombocythemia, and Primary Myelofi brosis167 Leukocytosis and Leukopenia168 Approach to the Patient with Lymphadenopathy and Splenomegaly169 Disorders of Phagocyte Function170 Eosinophilic Syndromes171 Approach to the Patient with Bleeding and Thrombosis172 Thrombocytopenia173 Von Willebrand Disease and Hemorrhagic Abnormalities of Platelet and Vascular Function174 Hemorrhagic Disorders: Coagulation Factor Defi ciencies175 Hemorrhagic Disorders: Disseminated Intravascular Coagulation, Liver Failure, and Vitamin K Defi ciency176 Thrombotic Disorders: Hypercoagulable States177 Transfusion Medicine178 Hematopoietic Stem Cell TransplantationSECTION XV: ONCOLOGY179 Approach to the Patient with Cancer180 Epidemiology of Cancer181 Cancer Biology and Genetics182 Myelodysplastic Syndromes183 The Acute Leukemias184 The Chronic Leukemias185 Non-Hodgkin Lymphomas186 Hodgkin Lymphoma 187 Plasma Cell Disorders 188 Amyloidosis189 Tumors of the Central Nervous System190 Head and Neck Cancer191 Lung Cancer and Other Pulmonary Neoplasms192 Neoplasms of the Esophagus and Stomach193 Neoplasms of the Small and Large Intestine194 Pancreatic Cancer195 Pancreatic Neuroendocrine Tumors196 Liver and Biliary Tract Cancers197 Tumors of the Kidney, Bladder, Ureters, and Renal Pelvis198 Breast Cancer and Benign Breast Disorders199 Gynecologic Cancers200 Testicular Cancer201 Prostate Cancer202 Malignant Tumors of Bone, Sarcomas, and Other Soft Tissue Neoplasms203 Melanoma and Nonmelanoma Skin Cancers204 Cancer of Unknown Primary OriginVOLUME IISECTION XVI: METABOLIC DISEASES205 Approach to Inborn Errors of Metabolism206 Disorders of Lipid Metabolism207 Glycogen Storage Diseases208 Lysosomal Storage Diseases209 Homocystinuria and Hyperhomocysteinemia210 The Porphyrias211 Wilson Disease212 Iron Overload (Hemochromatosis)SECTION XVII: NUTRITIONAL DISEASES213 Nutrition's Interface with Health and Disease214 Nutritional Assessment215 Protein-Energy Malnutrition216 Enteral Nutrition217 Malnutrition, Nutritional Assessment, and Nutritional Support in Adult Hospitalized Patients218 Vitamins, Trace Minerals, and Other Micronutrients219 Eating Disorders220 ObesitySECTION XVIII: ENDOCRINE DISEASES221 Approach to the Patient with Endocrine Disease222 Principles of Endocrinology223 Neuroendocrinology and the Neuroendocrine System224 Anterior Pituitary225 Posterior Pituitary226 Thyroid227 Adrenal Cortex228 Adrenal Medulla, Catecholamines, and Pheochromocytoma229 Diabetes Mellitus230 Hypoglycemia and Pancreatic Islet Cell Disorders231 Polyglandular Disorders232 Neuroendocrine Tumors and the Carcinoid Syndrome233 Disorders of Sexual Development234 The Testis and Male Hypogonadism, Infertility, and Sexual Dysfunction235 Ovaries and Pubertal Development236 Reproductive Endocrinology and InfertilitySECTION XIX: WOMEN'S HEALTH237 Approach to Women's Health238 Contraception239 Common Medical Problems in Pregnancy240 Menopause241 Intimate Partner Violence242 Approach to the Patient with Metabolic Bone Disease243 Osteoporosis244 Osteomalacia and Rickets245 The Parathyroid Glands, Hypercalcemia and Hypocalcemia246 Medullary Thyroid Carcinoma247 Paget Disease of Bone248 Osteonecrosis, Osteosclerosis/Hyperostosis, and Other Disorders of Bone249 Approach to the Patient with Allergic or Immunologic Disease250 Primary Immunodeficiency Diseases251 Allergic Rhinitis and Chronic Sinusitis252 Urticaria and Angioedema253 Systemic Anaphylaxis, Food Allergy, and Insect Sting Allergy254 Drug Allergy255 MastocytosisSECTION XXII: RHEUMATIC DISEASES256 Approach to the Patient with Rheumatic Disease257 Laboratory Testing in the Rheumatic Diseases258 Imaging Studies in the Rheumatic Diseases259 Connective Tissue Structure and Function260 Inherited Diseases of Connective Tissue261 The Systemic Autoinflammatory Diseases262 Osteoarthritis263 Bursitis, Tendinitis, and Other Periarticular Disorders and Sports Medicine264 Rheumatoid Arthritis265 The Spondyloarthropathies266 Systemic Lupus Erythematosus267 Systemic Sclerosis (Scleroderma)268 Sjoegren Syndrome269 Inflammatory Myopathies270 The Systemic Vasculitides271 Polymyalgia Rheumatica and Temporal Arteritis272 Infections of Bursae, Joints, and Bones273 Crystal Deposition Diseases274 Fibromyalgia, Chronic Fatigue Syndrome, and Myofascial Pain275 Systemic Diseases in Which Arthritis Is a Feature276 Surgical Treatment of Joint Diseases SECTION XXIII: INFECTIOUS DISEASES277 Introduction to Microbial Disease: Host-Pathogen Interactions278 The Human Microbiome279 Principles of Anti-Infective Therapy280 Approach to Fever or Suspected Infection in the Normal Host281 Approach to Fever and Suspected Infection in the Compromised Host282 Prevention and Control of Health Care-Associated Infections283 Approach to the Patient with Suspected Enteric Infection284 Approach to the Patient with Urinary Tract Infection285 Approach to the Patient with a Sexually Transmitted Infection286 Approach to the Patient before and after Travel287 Antibacterial Chemotherapy288 Staphylococcal Infections289 Streptococcus Pneumoniae Infections290 Nonpneumococcal Streptococcal Infections and Rheumatic Fever291 Enterococcal Infections292 Diphtheria and Other Corynebacterium Infections293 Listeriosis294 Anthrax295 Erysipelothrix Infections296 Clostridial Infections297 Diseases Caused by Non-Spore-Forming Anaerobic Bacteria298 Neisseria Meningitidis Infections299 Neisseria Gonorrhoeae Infections300 Haemophilus and Moraxella Infections301 Chancroid302 Cholera and Other Vibrio Infections303 Campylobacter Infections304 Escherichia Coli Enteric Infections305 Infections Due to Other Members of the Enterobacteriaceae, Including Management of Multidrug-Resistant Strains306 Pseudomonas and Related Gram-Negative Bacillary Infections307 Diseases Caused by Acinetobacter and Stenotrophomonas Species308 Salmonella Infections (Including Enteric Fever)309 Shigellosis310 Brucellosis311 Tularemia and Other Francisella Infections312 Plague and Other Yersinia Infections313 Whooping Cough and Other Bordetella Infections314 Legionella Infections315 Bartonella Infections316 Granuloma Inguinale (Donovanosis)317 Mycoplasma Infections 318 Diseases Caused by Chlamydiae 319 Syphilis320 Nonsyphilitic Treponematoses321 Lyme Disease322 Relapsing Fever and Other Borrelia Infections323 Leptospirosis324 Tuberculosis325 The Nontuberculous Mycobacteria326 Leprosy (Hansen Disease)327 Rickettsial Infections328 Zoonoses329 Actinomycosis330 Nocardiosis331 Systemic Antifungal Agents332 Histoplasmosis333 Coccidioidomycosis334 Blastomycosis335 Paracoccidioidomycosis336 Cryptococcosis337 Sporotrichosis338 Candidiasis339 Aspergillosis340 Mucormycosis341 Pneumocystis Pneumonia342 Mycetoma343 Dematiaceous Fungal Infections344 Antiparasitic Therapy345 Malaria346 African Sleeping Sickness347 Chagas Disease348 Leishmaniasis349 Toxoplasmosis350 Cryptosporidiosis351 Giardiasis352 Amebiasis353 Babesiosis and Other Protozoan Diseases354 Cestodes355 Schistosomiasis (Bilharziasis)356 Liver, Intestinal, and Lung Fluke Infections357 Intestinal Nematode Infections358 Tissue Nematode Infections359 Arthropods and Leeches360 Antiviral Therapy (Non-HIV)361 The Common Cold362 Respiratory Syncytial Virus363 Parainfluenza Viral Disease364 Influenza365 Adenovirus Diseases366 Coronaviruses367 Measles368 Rubella (German Measles)369 Mumps370 Cytomegalovirus, Epstein-Barr Virus, and Slow Virus Infections of the Central Nervous System371 Parvovirus372 Smallpox, Monkeypox, and Other Poxvirus Infections373 Papillomavirus374 Herpes Simplex Virus Infections375 Varicella-Zoster Virus (Chickenpox, Shingles)376 Cytomegalovirus377 Epstein-Barr Virus Infection378 Retroviruses Other Than Human Immunodeficiency Virus379 Enteroviruses380 Rotaviruses, Noroviruses, and Other Gastrointestinal Viruses381 Viral Hemorrhagic Fevers382 Arboviruses Causing Fever and Rash Syndromes383 Arboviruses Aff ecting the Central Nervous SystemSECTION XXIV: HIV AND THE ACQUIRED IMMUNODEFICIENCY SYNDROME384 Epidemiology and Diagnosis of Human Immunodeficiency Virus Infection and Acquired Immunodeficiency Syndrome385 Immunopathogenesis of Human Immunodeficiency Virus Infection386 Biology of Human Immunodeficiency Viruses387 Prevention of Human Immunodeficiency Virus Infection388 Antiretroviral Therapy of HIV/AIDS389 Infectious and Metabolic Complications of HIV and AIDS390 Gastrointestinal Manifestations of HIV and AIDS391 Pulmonary Manifestations of Human Immunodeficiency Virus and the Acquired Immunodeficiency Syndrome392 Skin Manifestations in Patients with Human Immunodeficiency Virus Infection 393 Hematology and Oncology in Patients with Human Immunodeficiency Virus Infection394 Neurologic Complications of Human Immunodeficiency Virus Infection395 Immune Reconstitution Inflammatory Syndrome in HIV/AIDSSECTION XXV: NEUROLOGY396 Approach to the Patient with Neurologic Disease397 Psychiatric Disorders in Medical Practice398 Headaches and Other Head Pain399 Traumatic Brain Injury and Spinal Cord Injury400 Mechanical and Other Lesions of the Spine, Nerve Roots, and Spinal Cord401 Regional Cerebral Dysfunction: Higher Mental Functions402 Alzheimer Disease and Other Dementias403 The Epilepsies404 Coma, Vegetative State, and Brain Death405 Disorders of Sleep406 Approach to Cerebrovascular Diseases407 Ischemic Cerebrovascular Disease408 Hemorrhagic Cerebrovascular Disease409 Parkinsonism410 Other Movement Disorders411 Multiple Sclerosis and Demyelinating Conditions of the Central Nervous System 412 Meningitis: Bacterial, Viral, and Other413 Brain Abscess and Parameningeal Infections414 Acute Viral Encephalitis415 Prion Diseases 416 Nutritional and Alcohol-Related Neurologic Disorders417 Congenital, Developmental, and Neurocutaneous Disorders418 Autonomic Disorders and Their Management 419 Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases420 Peripheral Neuropathies421 Muscle Diseases422 Disorders of Neuromuscular TransmissionXXVI: EYE, EAR, NOSE, AND THROAT DISEASES423 Diseases of the Visual System424 Neuro-Ophthalmology425 Diseases of the Mouth and Salivary Glands 426 Approach to the Patient with Nose, Sinus, and Ear Disorders427 Smell and Taste428 Hearing and Equilibrium429 Throat DisordersSECTION XXVII: MEDICAL CONSULTATION430 Principles of Medical Consultation431 Preoperative Evaluation432 Overview of Anesthesia433 Postoperative Care and Complications434 Medical Consultation in PsychiatrySECTION XXVIII: SKIN DISEASES435 Structure and Function of the Skin436 Examination of the Skin and an Approach to Diagnosing Skin Diseases437 Principles of Therapy of Skin Diseases438 Eczemas, Photodermatoses, Papulosquamous (Including Fungal) Diseases, and Figurate Erythemas439 Macular, Papular, Vesiculobullous, and Pustular Diseases440 Urticaria, Drug Hypersensitivity Rashes, Nodules and Tumors, and Atrophic Diseases441 Infections, Hyperpigmentation and Hypopigmentation, Regional Dermatology, and Distinctive Lesions in Black Skin442 Diseases of Hair and NailsAPPENDIX-LABORATORY REFERENCE INTERVALS AND VALUESReference Intervals and Laboratory Values
