Full Description
2014 BMA Medical Book Awards Highly Commended in Cardiology category! Cardiac Electrophysiology: From Cell to Bedside puts the latest knowledge in this subspecialty at your fingertips, giving you a well-rounded, expert grasp of every cardiac electrophysiology issue that affects your patient management. Drs. Zipes, Jalife, and a host of other world leaders in cardiac electrophysiology use a comprehensive, multidisciplinary approach to guide you through all of the most recent cardiac drugs, techniques, and technologies. Get well-rounded, expert views of every cardiac electrophysiology issue that affects your patient management from preeminent authorities in cardiology, physiology, pharmacology, pediatrics, biophysics, pathology, cardiothoracic surgery, and biomedical engineering from around the world.Visually grasp and easily absorb complex concepts through an attractive full-color design featuring color photos, tables, flow charts, ECGs, and more!Integrate the latest scientific understanding of arrhythmias with the newest clinical applications, to select the right treatment and management options for each patient.Stay current on the latest advancements and developments with sweeping updates and 52 NEW chapters - written by many new authors - on some of the hottest cardiology topics, such as new technologies for the study of the molecular structure of ion channels, molecular genetics, and the development of new imaging, mapping and ablation techniques.Get expert advice from Dr. Douglas P. Zipes - a leading authority in electrophysiology and editor of Braunwald's Heart Disease and the Heart Rhythm Journal - and Dr. Jose Jalife - a world-renowned leader and researcher in basic and translational cardiac electrophysiology.Access the full text online at Expert Consult, including supplemental text, figures, tables, and video clips.Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.
Contents
Part I. Structural and Molecular Bases of Ion Channel Function1 Voltage-Gated Sodium Channels and Electrical Excitablility of the Heart2 Calcium Channels in the Heart3 Voltage-Regulated Potassium Channels 4 Structural and Molecular Bases of Inward Rectifier Potassium Channel Function5 Mammalian Calcium Pumps in Health and Disease6 Structural and Molecular Bases of Sarcoplasmic Reticulum Ion Channel Function7 Structural and Molecular Bases of Mitochondrial Ion Channel Function8 Molecular Organization, Gating, and Function of Gap Junction ChannelsPart II. Biophysics of Cardiac Ion Channel Function9 Biophysics of Normal and Abnormal Cardiac Sodium Channel Function10 Regulation of Cardiac Calcium Channels11 KCNQ1/KCNE1 Macromolecular Signaling Complex: Channel Microdomains and Human Disease12 Structural Determinants and biophysical properties of hERG channel gating13 Molecular regulation of cardiac inward rectifier potassium channels by pharmacologic agents14 Cardiac Stretch-Activated Channels and Mechano-Electric Coupling15 Biophysical Properties of Gap Junctions16 Excitation-Contraction CouplingPart III. Intermolecular Interactions and Cardiomyocyte Electrical Function17 Ion Channel Trafficking in the Heart18 Macromolecular Complexes and Regulation of the Sodium Channel Nav1.519 Calmodulin and CaMKII as Ca2+ switches for cardiac ion channels20 Macromolecular Complexes and Cardiac Potassium Channels21 Reciprocity of Cardiac Sodium and Potassium channels in the control of Excitability and Arrhythmias22 The Intercalated Disc: A Molecular Network that Integrates Electrical Coupling, Intercellular Adhesion, and Cell Excitability23 Scaffolding Proteins and Ion Channel Diseases24 Epigenetics in Cardiac Rhythm DiseasesPart IV. Cell Biology of Cardiac Impulse Initiation and Propagation25 Cardiac Impulse is Initiated by a Coupled System of Membrane Ion Channels and Ca2+ Cycling Proteins26 Biological Pacing27 Intercellular Communication and Impulse Propagation28 Mechanisms of Atrioventricular Nodal Excitability and Propagation29 Cell Biology of the Specialized Cardiac Conduction System30 Cardiac Fibroblasts and ArrhythmogenesisPart V. Models of Cardiac Excitation31 Ionic Mechanisms of Atrial Action Potentials32 Models of the Ventricular Action Potential in Health and Disease33 Calcium Signaling in a Cardiomyocyte Models with Realistic Geometries34 Theory of Rotors and Arrhythmias35 Supraventricular Arrhythmias in a Realistic 3D model of the Human Atria36 Cardiac Electromechanical ModelsPart VI. Neural Control of Cardiac Electrical Activity37 Cav1.2 and ss-Adrenergic regulation of cardiac function38 cholinergic and constitutive regulation of atrial potassium channel39 Pulomnary vein ganglia and the neural regulation of the heart rate40 Neural activity and atrial tachyarrhythmias41 Sympathetic Innervation, Denervation, and cardiac arrhythmiasPart VII. Arrhythmia Mechanisms42 Dominant Frequency and the Mechanisms of Initiation and Maintenance of Atrial fibrillation43 Rotors in Human Atrial Fibrillation44 atrial ischemia and fibrillation45 The Molecular pathophysiology of atrial fibrillation46 Myofibroblasts, Cytokines and Persistent Atrial Fibrillation47 Role of The Autonomic Nervous System In Atrial Fibrillation48 Mechanisms of ventricular tachycardia and fibrillationPart VIII. Molecular Genetics and Pharmacogenomics49 Genetics of Atrial Fibrillation50 Mechanisms in Heritable Sodium Channel Diseases51 Inheritable Potassium Channel Disease52 Genetics and Cellular Mechanisms of the J Wave Syndromes53 Inheritable Phenotypes Associated with Altered Intracellular Calcium RegulationPart IX. Pharmacologic, Genetic and Cell Therapy of Ion Channel Dysfunction54 Pharmacologic Bases of Antiarrhythmic Therapy55 Pharmacogenomics of Cardiac Arrhythmias 56 Optogenetic Control of Heart Muscle57 Cell Therapy and Regeneartive ElectrophysiologyPart X. Diagnostic Evaluation58 Assessment of the Patient with a Cardiac Arrhythmia59 Differential Diagnosis of Narrow and Wide Complex Tachycardias60 Mapping and Navigation61 CT and MR Imaging for Electrophysiology62 Intracardiac Echocardiography for Electrophysiology63 Exercise -Induced Arrhythmias64 Cardiac Monitoring: Short- and Long-Term Recording65 Electrocardiographic Imaging in Patients with Acute Coronary Syndrome66 Head-up Tilt Table Testing67 Autonomic Testing and Cardiac Risk68 Monophasic Action Potential Recording 69 T-Wave Alternans70 Noninvasive Electrocardiographic Imaging of Human Ventricular Arrhythmias and Electrophysiologic Substrate71 Genetic TestingPart XI. Supraventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management72 Sinus Node Abnormalities73 Atrial Tachycardia74 Typical and Atypical Atrial Flutter: Mapping and Ablation75 Atrial Fibrillation: Paroxysmal, Persistent, and Permanent76 Preexcitation, Atrioventricular Reentry, and Variants77 Electrophysiological Characteristics of Atrioventricular Nodal Reentrant Tachycardia: Implications for the Reentrant Circuits78 Atrial Arrhythmias in Adults With Congenital Heart Disease79 Junctional TachycardiaPart XII. Ventricular Tacharrhythmias: Mechanisms, Clinical Features, and Management80 Premature Ventricular Complexes81 Outflow Tract Ventricular Tachyarrhythmias: Mechanisms, Clinical Features, and Management82 Fascicular Ventricular Arrhythmias83 Bundle Branch Reentry Tachycardia84 Ischemic Heart Disease85 Ventricular Tachycardia in Patients with Dilated Cardiomyopathy86 Ventricular Arrhythmias in Hypertrophic Cardiomyopathy87 Ventricular Tachycardias in Arrhythmogenic Right Ventricular Dysplasia/Cardiomyopathy88 VTs in Catecholaminergic Cardiomyopathy (Catecholaminergic Polymorphic Ventricular Tachycardia)89 Ventricular Arrhythmias in Heart Failure90 Ventricular Tachycardia in Noncompaction Cardiomyopathy91 Ventricular Arrhythmias in Takatsubo Cardiomyopathy92 Brugada Syndrome 1992-2012: Twenty Years of Scientific Progress93 Long and Short QT Syndromes94 Andersen-Tawil Syndrome95 Timothy Syndrome96 J Wave Syndromes97 Idiopathic Ventricular Fibrillation98 Sudden Infant Death Syndrome99 Sudden Cardiac Death in Adults100 Arrhythmias in Patients with Neurologic Disorders101 Drug-Induced Ventricular Tachycardia102 Ventricular Arrhythmias in Congenital Heart DiseasePart XIII. Syncope and AV Block103 Syncope104 Postural Orthostatic Tachycardia Syndrome105 Progressive Conduction System Disease106 Atrioventricular BlockPart XIV. Arrhythmias in Special Populations107 Sex Differences in Arrhythmias 108 Sudden Cardiac Deaths in Athletes, Including Commotio Cordis 109 Arrhythmias in Pediatric Population110 Sleep-Disordered Breathing and Arrhythmias Part XV. Pharmocologic Therapy111 Standard Antiarrhythmic Drugs112 New Antiarrhythmic Drugs and New Concepts for Old Drugs113 Impact of Nontraditional Antiarrhythmic Drugs on Sudden Cardiac Death 114 Prevention of Stroke with Atrial FibrillaitonPart XVI. Electrical Therapy115 Implantable Cardioverter Defibrillators: Technical Aspects 116 Implantable Cardioverter Defibrillators: Clinical Aspects117 Implantable Pacemakers 118 Cardiac Resynchronization Therapy119 Newer Applications of Pacemakers 120 Catheter Ablation: Technical Aspects121 Catheter Ablation: Clinical Aspects122 Ablation for Atrial Fibrillation123 Ablation of Supraventricular Tachyarrhythmias124 Catheter Ablation for Ventricular Tachycardia in Patients with Structural Heart Disease125 Special Ablation Approaches: Epicardial, Other126 Ablation in Pediatrics127 Catheter Ablation in Congenital Heart DiseasePart XVII. Surgery for Arrhythmias128 Atrial Fibrillation and Other SVTs129 Surgery for Ventricular ArrhythmiasPart XVIII. New Approaches130 Vagal Stimulation for Heart Failure131 Spinal Cord Stimulation for Heart Failure and Arrhythmias132 Left Atrial Occluders/Isolation
