Full Description
This interdisciplinary volume brings together many of the world's leading clinicians and researchers to discuss current and anticipated developments in the understanding of narcolepsy. The volume is broadly divided into four main sections: Section I - Etiology; Section II - Clinical Considerations; Section III - Psychosocial considerations; and, Section IV - Management. The areas covered include findings from research investigations on the genetic predisposition and pathophysiology, psychosocial aspects, and clinical management of narcolepsy by means of pharmacological and non-pharmacological methods. Special attention is paid to the translational aspects of narcolepsy. This volume is suitable for sleep disorders specialists and researchers, psychiatrists, neurologists, psychologists, social workers, behavioral scientists, graduate medical students, and any professionals and researchers interested in the interdisciplinary area of sleep medicine.Key features include the following: focus on issues faced in day-to-day clinical settings - helps to inform and change clinical practice; chapters address both clinical and research basis - highlights potential areas of future research; and, interdisciplinary and translational approach - suitable for a wide range of clinicians and biomedical professionals.
Contents
Foreword Clifford C. Saper, MD, PhD Preface Editors Credits and Acknowledgements Editors SECTION I: ETIOLOGY 1. Narcolepsy: Genetic predisposition and pathophysiology Emmanuel Mignot, MD, PhD. 2. Animal models of narcolepsy: Developments, findings, and perspectives Christopher M. Sinton, PhD. 3. Neuroimaging of narcolepsy Eric A. Nofzinger, MD. SECTION II: CLINICAL CONSIDERATIONS 4. Epidemiology of narcolepsy Lauren Hale, PhD. 5. Narcolepsy in Childhood Shalini Paruthi, MD. & Suresh Kotagal, MD. 6. Narcolepsy in the Older Adult Hrayr Attarian, MD. 7. Diurnal and nocturnal sleep in narcolepsy with cataplexy Yves Dauvilliers, MD, PhD & Giuseppe Plazzi, MD, PhD 8. Hypnagogic Hallucinations and Sleep Paralysis Armando D'Agostino, MD & Ivan Limosani, MD. 9. REM sleep behaviour disorder in narcolepsy with cataplexy. Giuseppe Plazzi, MD, PhD & Yves Dauvilliers, MD, PhD. 10. Narcolepsy and other comorbid medical illnesses Lori A. Panossian, MD & Alon Y. Avidan, MD, MPH. 11. Humor processing in human narcolepsy with cataplexy Aurelie Ponz & Sophie Schwartz, PhD. 12. Dreams in patients with narcolepsy Michael Schredl 13. Psychoanalysis and narcolepsy James F Pagel, MS, MD & Lawrence Scrima, PhD 14. Symptomatic narcolepsy or hypersomnia, with and without hypocretin (orexin) deficiency Kanbayashi T, Nakamura M, Shimizu T, & Seiji Nishino, MD, PhD. 15. Hypersomnias other than narcolepsy: Differential diagnosis Michel Billiard, MD. SECTION III: PSYCHOSOCIAL CONSIDERATIONS 16. Psychosocial impact of narcolepsy in children and adolescents Gregory Stores MA, MD, DPM, FRCPsych, FRCP. 17. Quality of life and psychosocial issues in narcolepsy Meeta Goswami BDS, MPH, PhD. 18. Narcolepsy, Intimacy and Sexuality Gila Lindsley, Ph.D. 19. Narcolepsy, driving and traffic safety Claire EHM Donjacour, Monique AJ Mets, Joris C Verster, PhD. 20. Memory and Cognition in Narcolepsy Christian Bellebaum, & Irene Daum, PhD. 21. Medico-legal aspects of disability in narcolepsy Francesca Ingravallo and Giuseppe Plazzi 22. Narcolepsy and mental health John Shneerson, MA, DM, MD, FRCP, FCCP SECTION IV: MANAGEMENT 23. Overview of management of narcolepsy Seiji Nishino, MD, PhD. 24. Modes of action of drugs related to narcolepsy: Pharmacology of wake-promoting compounds and anticataplectics Seiji Nishino, MD, PhD & Nozomu Kotorii, MD, PhD. 25. Modafinil/ Armodafinil in the Treatment of Narcolepsy Michael Thorpy, MD 26. Sodium oxybate in the treatment of narcolepsy Geert Mayer 27. Emerging treatments for narcolepsy Meredith Broderick MD & Christian Guilleminault MD, BiolD. 28. Non-pharmacologic Treatments of Narcolepsy Renee Monderer, MD, Shelby Freedman Harris, PsyD, CBSM. & Michael J. Thorpy, MD.
