Full Description
This volume will explore the latest findings in research into the genetics of breast and reproductive cancers, covering the epidemiological aspects of these cancers, their etiology, the effect of environment on genes and cancer etiology, and how research in this area can lead to development of preventative measures and treatments.
Contents
Recognition of Hereditary Breast and Reproductive Cancer Syndromes.- Cancer Genetics in the Clinic: The Challenges and Responsibilities of Counseling and Treating Women at Risk.- Management of Women with Inherited BRCA1 and BRCA2 Mutations.- Genetic etiology of breast and reproductive cancers.- Unclassified Variants in the Breast Cancer Susceptibility Genes BRCA1 and BRCA2.- Recent Advances in Understanding the Cellular Functions of BRCA1.- Recent Advances in Understanding the Cellular Functions of BRCA2.- Genetic Modifiers of Risk of BRCA1- and BRCA2-Related Breast and Ovarian Cancers.- Other Hereditary Breast Cancer Syndromes and Genes.- Ovarian and Endometrial Cancer in Patients with Hereditary Non-polyposis Colorectal Cancer Syndrome.- Somatic Alterations and Implications in Breast Cancer.- Somatic Genetic Development in Epithelial Ovarian Cancer.- Genes and the environment.- High-Frequency Low-Penetrance Alleles.- Host and Viral Genetics and Risk of Cervical Cancer.- Estrogen-Metabolizing Gene Polymorphisms, Genetic Susceptibility, and Pharmacogenomics.- The Future of Discoveries in Breast and Reproductive Cancers: The Genome and Epigenetics.
