Cardiovascular Proteomics Techniques : Applications for Clinical and Laboratory Research (Wiley Series on Mass Spectrometry)

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Cardiovascular Proteomics Techniques : Applications for Clinical and Laboratory Research (Wiley Series on Mass Spectrometry)

Banfi, Cristina (EDT)/ Desiderio, Dominic M. (EDT)/ Loo, Joseph A. (EDT)

ウェブストア価格 ¥52,673（本体¥47,885）
John Wiley & Sons Inc（2026/03発売）
外貨定価 US$ 250.00
ポイント 478pt

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製本 Hardcover:ハードカバー版／ページ数 592 p.
言語 ENG
商品コード 9781394211135

Full Description

Definitive reference on studying proteome biomarkers through cardiovascular disease pathophysiology and applied mass spectrometry

Cardiovascular Proteomics Techniques explores the intersection of cardiovascular disease pathophysiology and applied mass spectrometry to study proteome biomarkers. Leading experts provide a comprehensive overview of the physiopathology of cardiovascular system diseases, along with insights into their etiology and pathogenesis through proteomics. The book features thirty chapters covering a range of topics, including mass spectrometry, proteomics, atherosclerosis, heart biology, cardiovascular diseases, experimental models, network analysis, international proteomic initiatives, clinical proteomics, and sex and gender proteomics.

Cardiovascular Proteomics Techniques also includes in depth discussions on:

Antibody-based technologies for multiplexed protein detection and quantification, and their complementary role to mass spectrometry-based protein profiling.
New findings from proteomic analysis regarding the pathogenesis of atherosclerosis.
Emerging insights into the pathobiology of acute coronary syndromes.
Network medicine as a new paradigm for cardiovascular disease research and beyond, with potential applications in drug repurposing.
Recent advances in cardiovascular plasma proteomics and previously unexplored cardiac diseases, such as Takotsubo syndrome.

This book is ideal for researchers in mass spectrometry, proteomics, life sciences, and cardiovascular studies, Cardiovascular Proteomics Techniques aims to enhance our understanding of cardiovascular issues among clinicians and stimulate future developments in proteomics for the diagnosis and treatment of cardiovascular diseases.

List of Contributors xvii

1 Basic Concepts in Mass Spectrometry 1

2 Overview of Antibody-Based Technologies for Multiplexed Protein Detection and Quantification and Their Complementarity to Mass Spectrometry-Based Protein Profiling 31

3 General Features of the Cardiovascular System 67

4 Albumin and Cardiovascular Diseases 81

5 Platelets 109

6 The Role of Proteomics in Extracellular Vesicles Research in Cardiovascular Disease 141

7 Proteomics of Human Lipoproteins in Cardiovascular Diseases 183

8 Extracellular Matrix in Cardiovascular Pathophysiology 221

9 Pathogenesis of Atherosclerosis 261

10 Emerging Insights into the Pathobiology of Acute Coronary Syndromes 289

11 Valvular Heart Disease, from Physiopathology to Biomarker Discovery 321

12 Pathophysiology of Heart Failure 349

13 Diseases of the Aorta, Recent Insights 379

14 Unveiling Sex and Gender Differences in Cardiovascular Diseases 401

15 Trends in Mass Spectrometry Imaging for Cardiovascular Diseases 441

16 Network Medicine: A New Paradigm for Cardiovascular Disease Research and Beyond 459

17 Recent Advances in Cardiovascular Plasma Proteomics 497

18 Unexplored Cardiac Diseases: Takotsubo Syndrome 535

Index 553