Full Description
Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.Molecular, Cellular, and Tissue Engineering, the fourth volume of the handbook, presents material from respected scientists with diverse backgrounds in molecular biology, transport phenomena, physiological modeling, tissue engineering, stem cells, drug delivery systems, artificial organs, and personalized medicine.More than three dozen specific topics are examined, including DNA vaccines, biomimetic systems, cardiovascular dynamics, biomaterial scaffolds, cell mechanobiology, synthetic biomaterials, pluripotent stem cells, hematopoietic stem cells, mesenchymal stem cells, nanobiomaterials for tissue engineering, biomedical imaging of engineered tissues, gene therapy, noninvasive targeted protein and peptide drug delivery, cardiac valve prostheses, blood substitutes, artificial skin, molecular diagnostics in personalized medicine, and bioethics.
Contents
MOLECULAR BIOLOGYHistorical Perspective and Basics of Molecular Biology; Nathan R. Domagalski and Michael DomachBiomolecular Interactions; Gordon RuleRecent Advances in DNA Separations: Plasmid Purification, Rapid Electrophoresis, and Affinity-Based Recovery; James W. Schneider and Jeffrey M. SavardSystems and Technology Involving Bacteria; Nicole Bleckwenn and William BentleyExpression in Mammalian Cells; Tina Sauerwald and Michael BetenbaughDNA Vaccines Production and Engineering; Michael M. Domach, Jonathan W. Meade, and Mohammad A. AtaaiTRANSPORT PHENOMENA AND BIOMIMETIC SYSTEMSBiomimetic Systems: Concepts, Design, and Emulation; Robert J. FisherTransport/Reaction Processes in Biology and Medicine; E. N. LightfootMicrovascular Heat Transfer; James W. BaishFluid Dynamics for Bio Systems: Fundamentals and Model Analysis; Robert A. Peattie and Robert J. FisherAnimal Surrogate Systems; Michael L. Shuler, Sarina G. Harris, Xinran Li, and Mandy B. EschArterial Wall Mass Transport: The Possible Role of Blood Phase Resistance in the Localization of Arterial Disease; John M. Tarbell and Yuchen QiuTransport Phenomena and the Microenvironment; Robert J. Fisher and Robert A. PeattieTransport and Drug Delivery through the Blood-Brain Barrier and Cerebrospinal Fluid; Bingmei M. FuInterstitial Transport in the Brain: Principles for Local Drug Delivery; W. Mark SaltzmanSurfactant Transport and Fluid-Structure Interactions during Pulmonary Airway Reopening; David Martin, Anne-Marie Jacob, and Donald P. Gaver IIIPHYSIOLOGICAL MODELING, SIMULATION, AND CONTROLModeling Strategies and Cardiovascular Dynamics; Joseph L. Palladino, Gary M. Drzewiecki, and Abraham NoordergraafCompartmental Models of Physiological Systems; Claudio Cobelli, Giovanni Sparacino, Maria Pia Saccomani, Gianna Maria Toffolo, and Andrea CaumoCardiovascular Models and Control; Madhusudan Natarajan, Fernando Casas, and W.D. TimmonsRespiratory Models and Control; Chi-Sang PoonBiomimetic Approaches to Physiological Control; James J. Abbas and Amit AbrahamMethods and Tools for Identification of Physiologic Systems; Vasilis Z. MarmarelisModeling Vascular Vibrations: Autoregulation and Vascular Sounds; Gary M. Drzewiecki, John K.-J. Li, and Abraham NoordergraafExternal Control of Movements; Dejan B. Popovic' and Mirjana B. PopovicThe Fast Eye Movement Control System; John Denis EnderleA Comparative Approach to Analysis and Modeling of Cardiovascular Function; John K.-J. Li, Ying Zhu, and Abraham NoordergraafA Biomedical and Biophysical Approach to the Science in Cardiopulmonary Resuscitation; Gerrit J. Noordergraaf, Igor W. F. Paulussen, Alyssa Venema, Gert Jan Scheffer, and Abraham NoordergraafKinematic Modeling of Left Ventricular Diastolic Function; Leonid Shmuylovich, Charles S. Chung, and Sandor J. KovacsSTEM CELL ENGINEERING: AN INTRODUCTIONEngineering the Pluripotent Stem Cell Niche for Directed Mesoderm Differentiation; Celine L. Bauwens, Kelly A. Purpura, and Peter W. ZandstraCell Mechanobiology in Regenerative Medicine: Lessons from Cancer; Badriprasad Ananthanarayanan and Sanjay KumarSystems-Engineering Principles in Signal Transduction and Cell-Fate Choice; Karin J. Jensen, Anjun K. Bose, and Kevin A. JanesBiomaterial Scaffolds for Human Embryonic Stem Cell Culture and Differentiation; Stephanie Willerth and David SchafferStem Cells and Regenerative Medicine in the Nervous System; Shelly Sakiyama-ElbertStem Cells and Regenerative Medicine for Treating Damaged Myocardium; Rohini Gupta, Kunal Mehtani, Kimberly R. Kam, and Kevin E. HealyStem Cells and Hematopoiesis; Krista M. Fridley and Krishnendu RoySynthetic Biomaterials and Stem Cells for Connective Tissue Engineering; Ameya Phadke and Shyni VargheseDerivation and Expansion of Human Pluripotent Stem Cells; Sean P. PalecekBioreactors for Stem Cell Expansion and Differentiation; Carlos A. V. Rodrigues, Tiago G. Fernandes, Maria Margarida Diogo, Claudia Lobato da Silva, and Joaquim M. S. CabralTISSUE ENGINEERINGStrategic Directions; Peter C. JohnsonSilks; Monica A. Serban and David L. KaplanCalcium Phosphates; Kemal Sariibrahimoglu, Joop G.C. Wolke, Sander C.G. Leeuwenburgh, and John A. JansenEngineered Protein Biomaterials; Andreina Parisi-Amon and Sarah C. HeilshornSynthetic Biomaterials; Joshua S. Katz and Jason A. BurdickGrowth Factors and Morphogens: Signals for Tissue Engineering; A. Hari ReddiSignal Expression in Engineered Tissues; Martha O. Wang and John P. FisherPluripotent Stem Cells; Todd C. McDevitt and Melissa A. KinneyHematopoietic Stem Cells; Ian M. Kaplan, Sebastien Morisot, and Curt I. CivinMesenchymal Stem Cells; Pamela C. Yelick and Weibo ZhangNanobiomaterials for Tissue Engineering; Pramod K. Avti, Sunny C. Patel, Pushpinder Uppal, Grace O'Malley, Joseph Garlow, and Balaji SitharamanBiomimetic Approaches in Tissue Engineering; Indong Jun, Min Sup Kim, Ji-Hye Lee, Young Min Shin, and Heungsoo ShinMolecular Biology Techniques; X.G. Chen, Y.L. Fang, and W.T. GodbeyBiomaterial Mechanics; Kimberly M. Stroka, Leann L. Norman, and Helim Aranda-EspinozaMechanical Conditioning; Elaine L. Lee and Horst A. von RecumMicropatterned Biomaterials for Cell and Tissue Engineering; Murugan Ramalingam and Ali KhademhosseiniDrug Delivery; Prinda Wanakule and Krishnendu RoyGene Therapy; C. Holladay, M. Kulkarni, W. Minor, and Abhay PanditNanotechnology-Based Cell Engineering Strategies for Tissue Engineering and Regenerative Medicine Applications; Joaquim Miguel Oliveira, Joao Filipe Mano, and Rui Luis ReisCell Encapsulation; Stephanie J. BryantCoculture Systems for Mesenchymal Stem Cells; Song P. Seto and Johnna S. TemenoffTissue Engineering Bioreactors; Sarindr Bhumiratana, Elisa Cimetta, Nina Tandon, Warren Grayson, Milica Radisic, and Gordana Vunjak-NovakovicShear Forces; Jose F. Alvarez-Barreto, Samuel B. VanGordon, Brandon W. Engebretson, and Vasillios I. SikavitsasVascularization of Engineered Tissues; Monica L. Moya and Eric M. BreyBiomedical Imaging of Engineered Tissues; Nicholas E. Simpson and Athanassios SambanisMultiscale Modeling of In Vitro Tissue Cultivation; Kyriacos ZygourakisBone Engineering; Lucas A. Kinard, Antonios G. Mikos, and F. Kurtis KasperDental and Craniofacial Bioengineering; Hemin Nie and Jeremy J. MaoTendon and Ligament Engineering; Nicholas Sears, Tyler Touchet, Hugh Benhardt, and Elizabeth Cosgriff-HernandezCartilage Tissue Engineering; Emily E. Coates and John P. FisherTMJ Engineering; Michael S. DetamoreInterface Tissue Engineering; Helen H. Lu, Nora Khanarian, Kristen Moffat, and Siddarth SubramonyThe Bioengineering of Dental Tissues; Rena N. D'Souza, Katherine R. Regan, Kerstin M. Galler, and Songtao ShiTissue Engineering of the Urogenital System; In Kap Ko, Anthony Atala, and James J. YooVascular Tissue Engineering; Laura J. SuggsNeural Engineering; Yen-Chih Lin and Kacey G. MarraTumor Engineering: Applications for Cancer Biology and Drug Development; Joseph A. Ludwig and Emily BurdettARTIFICIAL ORGANSArtificial Heart and Circulatory Assist Devices; Gerson RosenbergCardiac Valve Prostheses; Arjunon, Neelakantan Saikrishnan, and Ajit P. YoganathanArtificial Lungs; Keith E. Cook, Timothy M. Maul, and William J. FederspielBlood Substitutes; Amy G. Tsai, Pedro Cabrales, and Marcos IntagliettaLiver Support Systems; Matthew S. Chang and Robert S. BrownPeritoneal Dialysis Equipment; Carlo Crepaldi, Francesca Katiana Martino, Maria Pia Rodighiero, and Claudio RoncoArtificial Skin and Dermal Equivalents; Dennis P. Orgill, Raul Cortes, and Ioannis V. YannasDRUG DESIGN, DELIVERY SYSTEMS, AND DEVICESPhysiological Barriers to Drug Transport; Fan YuanNucleic Acid Aptamers in Drug Delivery; Mark R. Battig, Jing Zhou, and Yong WangDendrimers for Drug Delivery; Giridhar Thiagarajan and Hamidreza GhandehariNoninvasive Targeted Protein and Peptide Drug Delivery; Pradeep K. Karla, Durga K. Paturi, Nanda K. Mandava, Animikh Ray, Sulabh Patel, Ranjana Mitra, and Ashim K. MitraEnvironment-Responsive Hydrogels for Drug Delivery; Byung Kook Lee, Jong-Ryoul Kim, Kinam Park, and Yong Woo ChoBiodegradable PLGA Scaffolds for Growth Factor Delivery; Yusef Khan and Cato LaurencinPERSONALIZED MEDICINEPhysiogenomic Contours: The Application of Systems Biology for Engineering Personalized Health Care; Andreas Windemuth, Richard L. Seip, and Gualberto RuanoThe Evolution of Massively Parallel Sequencing Technologies: Facilitating Advances in Personalized Medicine; Ian Toma, Georges St. Laurent, III, Samuel Darko, and Timothy A. McCaffreyComputational Methods and Molecular Diagnostics in Personalized Medicine; Roland Valdes, Jr. and Mark W. LinderNeed for Point-of-Care Testing Devices for Cardiac Troponin in Patients with Acute Coronary Syndromes; Alan H.B. Wu and Amy E. HerrETHICSAn Introduction to Bioethics and Ethical Theory for Biomedical Engineers; D. John Doyle
