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Full Description
Gleaning information from more than 100 experts in the field of cancer diagnosis, prognosis, and therapy worldwide, Cancer Biomarkers: Non-Invasive Early Diagnosis and Prognosis determines the significance of clinical validation approaches for several markers. This book examines the use of noninvasive or minimally invasive molecular cancer markers that are under development or currently in use. It deals with a majority of commonly prevalent cancers and can help anyone working in the health-care industry to recommend or develop early diagnostics, at-risk tests, and prognostic biomarkers for various cancers.
It explores the practice of determining biomarkers by their characteristics and relative methodologies, and presents the most recent data as well as a number of current and upcoming early diagnostic noninvasive molecular markers for many common cancers. It also considers the sensitivity and specificity of markers, biomarker market, test providers, and patent information.
Approximately 30-35 Cancer Specific Noninvasive Molecular Diagnostic Markers in a Single Volume
The book details the general and technical aspects of noninvasive cancer markers. It covers imaging, cutting-edge molecular technologies for biomarker development, and noninvasive or minimally invasive sources of molecular markers, as well as quality control and ethical issues in cancer biomarker discovery. It also provides a detailed account of brain, head and neck, and oral cancer markers, and provides information on a number of gastrointestinal cancers, lung cancer, and mesothelioma markers.
Emphasizes the Importance of Volatile Markers in Early Cancer Diagnosis
Presents noninvasive early molecular markers in urological cancers
Describes gynecological and endocrine cancer markers
Details noninvasive markers of breast, ovarian, cervical, and thyroid cancers
Addresses hematological malignancies
Contains information on noninvasive molecular markers in myelodysplastic syndromes, acute myeloid leukemia, Hodgkin's lymphoma, and multiple myeloma
Provides comprehensive information on diagnostic and prognostic biomarkers in cutaneous melanoma
This text considers molecular technologies for biomarker development, noninvasive or minimally invasive sources of molecular markers, and quality control and ethical issues in cancer biomarker discovery.
Contents
Part I General and Technical Aspects. Quality Control and Ethical Issues of Cancer Biomarker Discovery. Imaging Techniques in Cancer Diagnosis. Role of PET in Cancer Diagnosis. Innovative Tools for Early Detection of Cancer. Noninvasive Nanodiagnostics for Cancer. Mitochondrial DNA in Early Cancer Diagnosis and Screening. Circulating miRNA Biomarkers in Various Solid Cancers. Stem Cell Biomarkers in Early Diagnosis, Prognosis, and Therapy of Cancer. Salivary Biomarkers in Early Diagnosis and Monitoring of Cancer. Part II Brain and Head and Neck Cancers. Biomarkers for Brain Gliomas. Noninvasive Biomarkers in Head and Neck Squamous Cell Carcinoma. Biological Markers in Oral Squamous Cell Carcinoma. Part III Gastrointestinal Cancers. Biomarkers for Gastric Cancer and the Related Premalignant Conditions. Biomarkers in Esophageal Adenocarcinoma. Biomarkers for Diagnosis and Metastasis of Hepatocellular Carcinoma. Noninvasive Early Markers in Gallbladder Cancer. Noninvasive Early Markers in Pancreatic Cancer. Part IV Lung Cancer and Mesothelioma. Noninvasive Early Markers in Lung Cancer. Exhaled Volatile Organic Compounds as Noninvasive Early Molecular Markers in Lung Cancer: Bridging the Gap from Bench to Bedside. Part V Urological Cancers. Noninvasive Early Molecular Biomarkers in Kidney Cancer. Novel Oncomarkers Used for Earlier Detection of Bladder Carcinoma. Screening for Prostate Cancer: New Markers and Future Aspects. Part VI Gynecological and Endocrine Cancers. Early Biomarkers in Breast Cancer. Noninvasive Biomarkers in Ovarian Cancer. Early Markers for Neoplastic Lesions of the Uterine Cervix. Biomarkers in Diagnosis of Papillary Thyroid Carcinoma. Biomolecular Markers for Improving Management of Follicular and Medullary. Thyroid Cancer. Part VII Hematological Cancers. Biomarkers in Myelodysplastic Syndrome. Markers for Diagnosis, Prognosis, and Therapy of Acute Myeloid Leukemia. Biomarkers in Hodgkin's Lymphoma. Multiple Myeloma and Evolution of Novel Biomarkers and Therapies. Part VIII Melanoma. Diagnostic and Prognostic Biomarkers in Cutaneous Melanoma. Index.
