基本説明
Defines and explains the clinical relevance of an important geriatric syndrome: Sarcopenia.
Full Description
Edited and written by world experts in the field, this book defines and explains the clinical relevance of an important geriatric syndrome: Sarcopenia. The book covers all recent scientific evidence and treatment options including interventions to improve sarcopenia, nutritional approaches to treat sarcopenia and the future of drug treatments.
Contents
List of Contributors vii Preface xi 1 Epidemiology of Muscle Mass Loss with Age 1 Marjolein Visser 2 Definitions of Sarcopenia 8 John E. Morley and Alfonso J. Cruz-Jentoft 3 Muscle Biology and mTORC1 Signaling in Aging 20 Blake B. Rasmussen and Elena Volpi 4 The Role of the Nervous System in Muscle Atrophy 41 Minal Bhanushali, Robin Conwit, Jeffrey Metter and Luigi Ferrucci 5 Nutrition, Protein Turnover and Muscle Mass 59 Stephane Walrand, Christelle Guillet and Yves Boirie 6 The Complex Relation between Muscle Mass and Muscle Strength 74 Todd M. Manini, David W. Russ and Brian C. Clark 7 Is Sarcopenia a Geriatric Syndrome? 104 Jean-Pierre Michel and Alfonso J. Cruz-Jentoft 8 Adverse Outcomes and Functional Consequences of Sarcopenia 114 David R. Thomas 9 A Lifecourse Approach to Sarcopenia 125 Avan Aihie Sayer 10 Cachexia and Sarcopenia 141 Maurizio Muscaritoli, Simone Lucia and Filippo Rossi Fanelli 11 Sarcopenia and Frailty 154 Cornel C. Sieber 12 Sarcopenia, Osteoporosis and Fractures 168 Tommy Cederholm 13 Sarcopenic Obesity 181 Mauro Zamboni, Andrea P. Rossi and Elena Zoico 14 Imaging of Skeletal Muscle 193 Thomas F. Lang 15 Measurements of Muscle Mass, Equations and Cut-off Points 205 Marjolein Visser and Laura Schaap 16 Measurement of Muscle Strength and Power 226 Michael Drey and Jurgen M. Bauer 17 Measurements of Physical Performance 238 Rolland Yves, Gabor Abellan van Kan and Matteo Cesari 18 Exercise Interventions to Improve Sarcopenia 252 Mark D. Peterson and Jos'e A. Serra-Rexach 19 Nutritional Approaches to Treating Sarcopenia 275 Douglas Paddon-Jones and Luc van Loon 20 The Future of Drug Treatments 296 Francesco Landi, Yves Rolland and Graziano Onder 21 Sarcopenia: Is It Preventable? 324 Maurits Vandewoude and Ivan Bautmans Index 339
