Full Description
This detailed book explores advanced techniques specifically designed to address the difficulties and complexities associated with molecular biological inquiry in microgravity conditions. Beginning with the specific space environment and unique systems biology constraints in space, the volume continues with methods on cells and pathways, tissues and physiological apparatus, and specific technological approaches and personalized-based approaches. Written for the highly successful Methods in Molecular Biology series, chapters provide the kind of detail and implementation advice that translates to success in the laboratory.
Practical and authoritative, Biomedicine and Biotechnology in Space: Molecular Methods serves as an ideal guide for researchers seeking insights into this very complex field of scientific study.
Contents
Biomedicine and Biotechnology in Space: An Introduction.- Hypergravity, Microgravity, and Animal Research.- Assessing the Effects of Microgravity on Eukaryotic Cells Using a Statistical Thermodynamic Approach.- Multiscale Modeling and Systems Biology in Microgravity Investigations.- Transcriptomics in Space: A Basic R Pipeline for Analyzing Bulk RNA-Sequencing Data.- A Systems Biology Approach to Discovery and Validation of MicroRNA Signature Health Risks Associated with the Space Environment.- The Cytoskeleton in Space.- Epigenetics in Space: The Dynamic Cellular Response.- Modulation of Cell-to-Cell Adhesion and Interaction with the Extracellular Matrix in Microgravity Conditions.- Histochemistry and Immunohistochemistry in Space Biology: Analysis of the Functional Morphology of the Tissue Microenvironment.- Ovarian Reproductive and Endocrine Function Investigated in Microgravity Environment.- Defining Microbiome Impact on Host Physiology During Spaceflight Using Caenorhabditis elegans.- 3D Bioprinted Tumor Constructs for Photothermal Therapy: Emerging Opportunities in Microgravity Research.- Regenerative Medicine in Space: Advancing Bone Repair with Adipose Stem Cells and Bone-on-Chip Technology.- Integrated Platforms to Further Advance Space Biology Research.- Precision Medicine in Astronauts: Principles and Targets in Molecular Assessment.
