Full Description
This book analyzes liquid biopsy applications in cancer and other diseases. Chapters guide readers through the latest technologies and analysis methods for liquid biopsy,liquid biopsy in cancer, role of liquid biopsies in rheumatoid arthriti, cell-free circulating DNA profiling in patients with skin diseases, circulating non-coding RNAs, and exomes. Written in the format of the highly successful Methods in Molecular Biology series, each chapter includes an introduction to the topic, lists necessary materials and reagents, includes tips on troubleshooting and known pitfalls, and step-by-step, readily reproducible protocols.
Authoritative and cutting-edge, Liquid Biopsies: Methods and Protocols aims to attract more researchers and clinicians to study the diagnosis, immunotherapy, and prognosis of cancer and other diseases with liquid biopsy analysis.
Contents
The Protocol of Circulating Tumor Cell Detection.- Cell-free RNA sequencing from biofluid samples.- Detection of Circulating Tumor DNA in plasma using Targeted Sequencing.- Exosomal RNA sequencing from body fluid samples.- Detection of micro-organisms in body fluid samples.- The Interactome of Protein, DNA and RNA.- Liquid biopsy in bladder cancer.- CSF Biopsy in Glioma: ABrief Review.- Diagnosis, Monitoring, and Prognosis of Liquid Biopsy in Cancer Immunotherapy.- The implication of liquid biopsy in the non-small cell lung cancer: potential and expectation.- Cell-free DNA, MicroRNAs, Proteins and Peptides as liquid biopsy biomarkers in prostate cancer and bladder cancer.-Identification of plasma metabolites associated with lung cancer survival.- The detection of exosomal PD-L1 in peripheral blood.- Liquid Biopsy in Hepatocellular Carcinoma.- Role of circulating tumor DNA in colorectal cancer.- The value of cell-free circulating DNA profiling in patients with skin diseases.- The value of cell-free circulating DNA profiling in patients with skin diseases.- Circulating non-coding RNAs and exosomes: liquid biopsies for monitoring preeclampsia.- Liquid Biopsy in Coronary Heart Disease.- The diagnostic and prognostic value of synovial fluid analysis in joint diseases.- Liquid biopsy, a potential new detection method in heart allograft rejection.- Potential value and application of liquid biopsy in tumor, neurodegeneration and muscle degenerative diseases.- Liquid biopsy in adverse neurodevelopment of children: problems and prospects.- Advances of liquid biopsy for diagnosis of atrial fibrillation and its recurrence after ablation in clinical application.
