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Full Description
Together, these three seminal reference works provide all the information needed to work with pigs in laboratory settings.
For three decades, Swine in the Laboratory has been the most respected practical technical guide for medical and veterinary researchers using swine as experimental animals. Sponsored by the American College of Laboratory Animal Medicine (ACLAM), it continues to be the most authoritative source of scientific and technical information on the use of domestic and miniature swine in research.
Anatomy and Histology of the Pig is the first guide specific to swine since 1982. The high-quality, detailed full-color illustrations are accompanied by written material specific to each porcine anatomic section, with English-labeled terms for the various anatomic structures. The book covers all the major areas of interest in swine, including cardiovascular, digestive, neurologic, and thoracic structures. Differences between domestic and miniature pigs are discussed and a full-color histology section concludes the book.
Finally, the second edition of The Minipig in Biomedical Research is a comprehensive resource for research scientists on the use of the minipig in basic and applied biomedical research. Written by experts in the field, coverage extends from the minipig's origins, anatomy, genetics, immunology, pathology and physiology to its welfare, health, and husbandry; practical dosing and examination procedures; surgical techniques; and all areas of toxicity testing and the uses of the minipig as a disease model. The book represents the state of the art, recognising the growing influence of Artificial Intelligence, and where appropriate, relevant databases are referenced.
Contents
Swine in the Laboratory
Biology, Handling, Husbandry, and Anatomy. Anesthesia, Analgesia, and Perioperative Care. Wound Closure and Integument. Gastrointestinal Procedures. Liver and Biliary System. Pancreas and Spleen. Urinary System and Adrenal Glands. The Reproductive System. Cardiothoracic and Vascular Surgery/Chronic Intravascular Catheterization. Head and Neck Surgery/Central Nervous System. Musculoskeletal System and Orthopedic Procedures. Cardiovascular Catheterization, Electrophysiology, and Imaging Laboratory Procedures. Endoscopy and Minimally Invasive Surgery. Xenotransplantation and Transgenic Technologies. Toxicology. Radiobiology. Imaging Techniques with CT, MRI, PET, and SPECT. Ossabaw Island Miniature Swine: Metabolic Syndrome and Cardiovascular Assessment. Swine in Cancer Research. Necropsy on Research Swine. Use of Swine in Biomedical Research.
Anatomy and Histology of the Pig
1. Introduction and General Anatomy 2. Anatomic Atlas 3. Normal Histology of the Pig
The Minipig in Biomedical Research 2E
Chapter 0 Introduction Chapter 1 - The Göttingen Minipig Chapter 2 - Sinclair Nanopig Chapter 3 - The Yucatan minipig in research : A compendium Chapter 4 - The Ossabaw miniature pig Chapter 5 - The Bama minipig Chapter 6 - Husbandry and Management Chapter 7 - Diseases of minipigs Chapter 8 - Animal welfare standards around the world. AAALAC and beyond Chapter 9 - Common surgical procedures for minipigs Chapter 10 - Species selection for nonclinical programmes Chapter 11 - Regulatory aspects of the use of minipigs in the development of pharmaceuticals for human use Chapter 12 - Regulatory Acceptance of the Minipig in Non-Pharmaceutical Industry and Research Chapter 13 - The Minipig and Pig in Medical Device Research Chapter 14 - Dermal toxicology in the minipig : skin architecture, metabolism, penetration and toxicological and pharmacological methods Chapter 15 - The Gastrointestinal Tract Chapter 16 - Central and Peripheral Nervous Systems Chapter 17 - The kidney Chapter 18 - Skeletal system Chapter 19 - The minipig in regulatory guidelines for DART and juvenile toxicity studies Chapter 20 - The minipig eye as a model for preclinical toxicology Chapter 21 - Oral Biology and Dental Models Chapter 22 - The use of the minipig as a suitable species for inhalation administration Chapter 23 - The Minipig in Safety Pharmacology Chapter 24 - Spontaneous/background pathology of minipigs Chapter 25 - Immunological tools for minipig research Chapter 26 - Immunotoxicology Chapter 27 - Osteoporosis Model in Minipigs Chapter 28 - Use of minipigs in advanced therapy development Chapter 29 - Xenotransplantation Chapter 30 - Digital biomarkers and AI
