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Full Description
This book comprehensively covers the principles, methodology, and applications of network pharmacology in drug discovery, pharmacovigilance, and precision medicine. The initial chapters guide readers through the principles and processes, detailing step-by-step procedures such as creating networks for compounds and disease targets. The intersection of network pharmacology with quantitative systems pharmacology is explored, along with an examination of various databases and essential software tools for conducting network pharmacological studies. It discusses the role of machine learning and AI in network pharmacology, delves into the application of systems biology for understanding complex diseases' pathogenesis, and highlights its contribution to drug discovery and repurposing. The book reviews the role of network pharmacology in different stages of drug discovery and repurposing, emphasizing its application in shaping drug formulations for enhanced efficacy and reduced side effects. Towards the end, it addresses translatability issues in drug discovery and repositioning predictions in clinical practice. This book caters to professionals, researchers, and advanced students in the pharmaceutical sciences.
Key Features
1) Presents principles, methodologies, and applications of network pharmacology.
2) Explores the intersection of network pharmacology with quantitative systems pharmacology.
3) Highlights the role of machine learning and artificial intelligence in network pharmacology.
4) Reviews the role of network pharmacology in different stages of drug discovery and repurposing.
5) Examines the pivotal role of network pharmacology in precision medicine
Contents
Introduction to Network Pharmacology. 2. Principles and Processes involved in Network Pharmacology. 3. Quantitative Systems Pharmacology. 4. Network Pharmacology Databases and Software's. 5. Application of machine learning and artificial intelligence-based tools in network pharmacology. 6. Role of system biology in drug discovery and repurposing. 7. Role of network pharmacology in herbal drug discovery and development. 8. Case Study of Network Pharmacology in Pharmacovigilance. 9. Network Pharmacology in Pharmaceutical Formulations. 10. Role of Network Pharmacology in Precision Medicine. 11. Unveiling Drug-Target Interactions and Disease Pathways: Leveraging Cytoscape for Comprehensive Network Pharmacology and Addressing Challenges. 12. Cherylline, a phytoconstituent of Crinum moorei, targets MAO-A in Alzheimer's disease: Network pharmacology integrated with molecular docking and dynamics studies. 13. Case Studies on Network Pharmacology In Predicting The Mechanism Of Herbal Drugs. 14. Ethics in Network Pharmacology: Challenges and Opportunities. 15. Applications, Current Challenges, and Future Perspectives of Network Pharmacology. 16. Network pharmacology: illuminating the path towards exploring the herbal formulations of the Indian Traditional Ayurvedic System. 17. Role of Network Pharmacology in Medicinal Chemistry. 18. Role of Network Pharmacology in Homoepathy. 19. Role of Network Pharmacology in Traditional Chinese Medicine (TCM) System.