Full Description
This important and exciting atlas shows with unprecedented resolution the development of the human embryo from fertilization to the end of pre-implantation development. Technology can now capture dynamic changes at the subcellular level that drive embryogenesis and development, allowing the whole team in reproductive medicine to move on from traditional imaging of fixed specimens or classic light microscopy to seeing, as if in 3D and real time, the process of fertilization and development of the human embryo - and of developmental defects. The human embryo research documented here will be of paramount importance for reproductive health, offering the chance to advance fertility treatments, genetic disease prevention, and our understanding of early human development.
Contents
Preface. Imaging preimplantation embryos with cellular resolution. Fertilization and early cell cleavages. Embryo compaction and polarization. Lineage segregation. Blastocyst morphogenesis and hatching. Changes in cellular organization during preimplantation development. Identifying cellular features indicating compromised embryo development.
