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Full Description
At the frontier of modern medicine lies a revolution in drug delivery systems that operates at the scale of billionths of a meter. Nanocarriers for Nucleic Acids and Proteins presents a comprehensive exploration of these groundbreaking technologies that are reshaping therapeutic approaches across medical science.
From fundamental concepts to cutting-edge applications, this comprehensive volume brings together world-class researchers to provide an in-depth examination of:
Design principles and characteristics of various nanocarrier systems
Advanced delivery mechanisms for nucleic acids and proteins
Breakthrough applications in gene therapy and cancer immunotherapy
Critical aspects of translating laboratory success to clinical implementation
Featuring detailed coverage of lipid-based, polymer-based, inorganic, and bio-inspired nanocarriers, this essential resource bridges the gap between theoretical understanding and practical application. Whether you are developing new therapeutic approaches, optimizing delivery systems, or exploring the frontiers of nanomedicine, this comprehensive guide provides the insights and frameworks needed to advance your work.
Contents
Chapter 1: Introduction to Nanocarriers for Nucleic Acids and Proteins.
Juan C. Cruz, Yashwant V Pathak and Luis H. Reyes
Chapter 2: Design Principles of Nanocarriers: Size, Shape, and
Surface Properties, Stimuli-Responsive Systems.
Juan C. Cruz, Luis H. Reyes
Chapter 3: Lipid-Based Nano Carriers for Nucleic Acids and Proteins: Liposomes, solid lipid nanoparticles, nanostructured lipid carriers
Biswajit Basu, Ayon Dutta, Dipanjana Ash, Bhupendra Prajapati*, Swarupananda Mukherjee
Chapter 4: Polymer-based nanocarriers: dendrimers, polymeric micelles, hydrogels
Juan C. Cruz and Luis H. Reyes
Chapter 5: Inorganic nano carriers: gold nanoparticles, iron nanoparticles, silica nanoparticles, quantum dots
Juan C. Cruz,and Luis H. Reyes
Chapter 6: Carbon-based nano carriers: Carbon nanotubes, graphene oxide, fullerenes, and Carbon dots
Cristian F. Rodríguez, Paula Guzmán-Sastoque, Coryna Rodriguez-Bazurto, Juan C. Rojas-Hernández, Luis H. Reyes, Juan C. Cruz
Chapter 7 : Virus Inspired Nano Carriers
Ankita Alice Singh, Seema Kohli
Chapter 8: Nucleic acid nano carriers DNA nanostructures, RNA nanostructures, hybrid nucleic acid systems
Komal Parmar, and Jayvadan Patel
Chapter 9 : Protein-based nano carriers: protein cages, self-assembling peptides, fusion proteins,
Nishant B. Chopade, Prashant K. Deshmukh,and Mahesh P. More
Chapter 10 : Nanocarrier Functionalization Strategies: Targeting Ligands, Imaging Agents, stimuli-responsive Elements
Sampada Satish Shinde, Bhavna Sonule, Lalit Kumar
Chapter 11: Delivery of nucleic acids using nano carriers:
siRNA and miRNA delivery, mRNA and DNA delivery, CRISPR-Cas systems
Paula Guzmán-Sastoque,María Camila Monsalve, Cristian F. Rodríguez, Stiven Castellanos,Juan C. Cruz, and Luis H. Reyes
Chapter 12: Delivery of proteins using nanocarriers: enzymes, antibodies and growth factors
Jennifer Suurbaar,
Frederick Sarfo-Antwi Seth Kwabena Amponsah,
Chapter 13 : Nanocarrier in gene therapy
Sinjini Sarkar, Swarupananda Mukherjee, Shilpa Chatterjee, Biswajit Basu, Dipanjan Karati, Bhupendra Prajapati
Chapter 14: Nanocarriers in Cancer Immunotherapy: Personalized Cancer Vaccines, Immune Checkpoint Modulation,
Adoptive T-Cell Therapy
Vineet Mahajan and Yashwant Pathak
Chapter 15: Future perspectives and challenges: clinical translation and regulatory aspects, scale-up and
manufacturing, ethical considerations
Aparoop Das, Kalyani Pathak Riya Saikia, Manash Pratim Pathak,Urvashee Gogoi, Dibyajyoti Das, Jon Jyoti Sahariah, Saptasikha Gogoi and Sukanya Sonowa
Chapter 16: Regulatory Toxicology of Biologics: Safeguarding Health in Biotherapeutic Development
Satish Rojekar, Nishant Talati, Shahin Vhora,
Nidhi Kotadiya, Mitul Talala, Ruby Chrisitan, Vikas Jain, Tosha Pandya, Disha Suthar, and Kinjal Parikh
