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Full Description
With step-by-step methods of drug production and knowledge of major unit operations and key concepts of pharmaceutical engineering, this guide will help to improve communication among the varied professionals working in the pharmaceutical industry. The updated volume reflects the acceleration occurring in processes to support new product development as the revolution initiated by characterization of the human genome at the turn of the millennium has an impact in transforming the treatment of disease.
Key Features
Thoroughly revised and expanded professional text illustrates how materials that are being processed have evolved as the understanding of the cell biology and biochemistry of disease has improved and new treatments have emerged based on the products of biotechnology.
Emphasizes the importance of pharmaceutical engineering and addresses the advances in disease therapy including their implications for pharmaceutical process engineering.
Each topic has been updated to reflect new developments occurring in the last decade.
Describes biosynthesis, of particular relevance to proteins and nucleic acids as well as gene transfer by transfection and editing used currently in cell therapies for a variety of rare diseases.
Exciting new chapter on artificial intelligence and machine learning as tools for process optimization.
Contents
Foreword. About the Author. Chapter 1: Introduction. Chapter 2: Pharmaceutical Quality Control and Assurance. Chapter 3: Processes. Chapter 4: Bioprocessing. Chapter 5: Crystallization. Chapter 6: Particle Size, Reduction and Classification. Chapter 7: Mixing. Chapter 8: Solid Dosage Forms. Chapter 9: Solid-Liquid Extraction. Chapter 10: Filtration. Chapter 11: Evaporation and Distillation. Chapter 12: Air Conditioning and Humidification. Chapter 13: Drying. Chapter 14: Sterilization. Chapter 15: Fluid Flow. Chapter 16: Heat Transfer. Chapter 17: Mass Transfer. Chapter 18: Powders. Chapter 19: Conclusion. Index



