Full Description
This indispensable resource provides a comprehensive guide to the most impactful studies that have shaped the field of neurosurgery. It distils the key findings and clinical relevance of 50 landmark papers across the full spectrum of neurosurgical subspecialties.
Designed with the needs of neurosurgery residents, fellows, and junior faculty in mind, this book provides a concise, high-yield format that is ideal for preparing for the ABNS oral board exam, FRCS, and FRCSC certifications. Each chapter is authored by leading experts in the field, offering unique insights into the rationale, methodology, and clinical impact of these pivotal studies. Key points are highlighted in a clear and concise manner, supported by tables, line diagrams, and practical commentary to ensure rapid comprehension and retention.
The challenge of navigating the ever-increasing neurosurgical literature can be daunting and this one-stop resource for evidence-based practice helps readers access the core literature. Whether you are preparing for certification exams or seeking to deepen your understanding of the field, 50 Landmark Papers Every Neurosurgeon Should Know is your definitive guide to the foundational studies that continue to shape neurosurgical practice worldwide making it an essential tool for neurosurgery trainees, practicing neurosurgeons, and educators seeking to enhance their knowledge and improve outcomes in patient care.
Contents
Section One - Tumour
1 - Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
2 - MGMT gene silencing and benefit from temozolomide in glioblastoma
3 - Fluorescence-guided surgery with 5-aminolevulinic acid for resection of malignant glioma: a randomised controlled multicentre phase III trial
4 - A randomized trial of surgery in the treatment of single metastases to the brain
5 - Prognostic factors for survival in adult patients with cerebral low-grade glioma
6 - Long-term outcomes after supratotal resection of diffuse low-grade gliomas: a consecutive series with 11-year follow-up
7 - The recurrence of intracranial meningiomas after surgical treatment
8 - Phase I/II study of resection and intraoperative cesium-131 radioisotope brachytherapy in patients with newly diagnosed brain metastases
9 - Natural history of asymptomatic colloid cysts of the third ventricle
Section Two - Vascular
10 - Surgical Risk as Related to Time of Intervention in the Repair of Intracranial Aneurysms
11 - International Subarachnoid Aneurysm Trial (ISAT) of neurosurgical clipping versus endovascular coiling in 2143 patients with ruptured intracranial aneurysms: a randomised trial
12 - International Study of Unruptured Intracranial Aneurysms Investigators. (ISUIA2) Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment.
13 - Effect of oral nimodipine on cerebral infarction and outcome after subarachnoid haemorrhage: British aneurysm nimodipine trial
14 - A proposed grading system for arteriovenous malformations
15 - Early decompressive surgery in malignant infarction of the middle cerebral artery: a pooled analysis of three randomised controlled trials
16 - Benefit of Carotid Endarterectomy in Patients with Symptomatic Moderate or Severe Stenosis. North American Symptomatic Carotid Endarterectomy Trial (NASCET)
17 - Trial of Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH)
Section Three - Paediatrics18 - Randomized trial of cerebrospinal fluid shunt valve design in pediatric hydrocephalus.
19 - Endoscopic third ventriculostomy in the treatment of childhood hydrocephalus
20 - Antibiotic or silver versus standard ventriculoperitoneal shunts (BASICS): a multicentre, single-blinded, randomised trial and economic evaluation
21 - A Randomized Trial of Prenatal versus Postnatal Repair of Myelomeningocele (MOMS trial)
22 - Incidence and evolution of subependymal and intraventricular hemorrhage: a study of infants less than 1,500 gm.
23 - Intrinsic brain-stem tumors of childhood: surgical indications
24 - Molecular subgroups of medulloblastoma: the current consensus
25 - Pial Synangiosis for Moyamoya Syndrome in Children
26 - Hypothermia Therapy after Traumatic Brain Injury in Children
Section Four - Functional/Epilepsy
27 - The first clinical trial to establish deep brain stimulation of the subthalamic nucleus as an evidence-based treatment for Parkinson's disease
28 - The Long-term Outcome of Microvascular Decompression for Trigeminal Neuralgia
29 - A Randomized, Controlled Trial of Surgery for Temporal-Lobe Epilepsy
30 - Early Identification of Refractory Epilepsy
31 - Vagus nerve stimulation for treatment of partial seizures: 1. A controlled study of effect on seizures
32 - Intracarotid injection of sodium amytal for the lateralization of cerebral speech dominance
Section Five - Head Trauma
33 - Assessment of coma and impaired consciousness. A practical scale
34 - Traumatic Acute Subdural Hematoma: Major Mortality Reduction in Comatose Patients Treated within Four Hours
35 - Use of drains versus no drains after burr-hole evacuation of chronic subdural haematoma: a randomised controlled trial
36 - Significance of intracranial hypertension in severe head injury
37 - A randomized, double-blind study of phenytoin for the prevention of post-traumatic seizures
38 - Final results of MRC CRASH, a randomised placebo-controlled trial of intravenous corticosteroid in adults with head injury-outcomes at 6 months.
39 - Trial of Decompressive Craniectomy for Traumatic Intracranial Hypertension (RESCUEicp trial).
40 - Surgical Management of Acute Epidural Hematomas
Section Six - Spine Trauma
41 - Validity of a Set of Clinical Criteria to Rule Out Injury to the Cervical Spine in Patients with Blunt Trauma
42 - The subaxial cervical spine injury classification system: a novel approach to recognize the importance of morphology, neurology, and integrity of the disco-ligamentous complex
43 - A new classification of thoracolumbar injuries: the importance of injury morphology, the integrity of the posterior ligamentous complex, and neurologic status
44 - A Clinical Practice Guideline for the Management of Patients With Acute Spinal Cord Injury: Recommendations on the Use of Methylprednisolone Sodium Succinate
Section Seven - Spine
45 - Effect of High-dose Dexamethasone in Carcinomatous Metastatic Spinal Cord Compression Treated with Radiotherapy: a Randomised Trial
46 - Direct Decompressive Surgical Resection in the Treatment of Spinal Cord Compression Caused by Metastatic Cancer: A Randomised Trial
47 - Surgical vs nonoperative treatment for lumbar disc herniation: the Spine Patient Outcomes Research Trial (SPORT): a randomized trial
48 - Cauda Equina Syndrome Secondary to Lumbar Disc Herniation: A Meta-Analysis of Surgical Outcomes
49 - Surgical vs nonsurgical therapy for lumbar spinal stenosis
50 - The anterior approach for removal of ruptured cervical disks
