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Full Description
Synthesis is one of the distinguishing features of chemistry as a science. It is the synthetic chemist who uses their intimate understanding of molecular structure and properties to produce materials of great value to society. Thus, it is important for students of chemistry to study synthesis and acquire a working knowledge that enables them to address the following question: given a specific molecular target, how does one formulate a plan for its synthesis? This synthesis primer provides students who have taken introductory organic chemistry with a set of tools that can be used to plan a synthesis. It may be used in conjunction with a synthetic methods course, or it can stand alone.
Features:
Provides students who have taken introductory organic chemistry with a set of tools that can be used to plan a synthesis
Serves to help organic chemists at all levels to better understand published syntheses
Focuses on natural products, their complexity, and diverse structures which challenge and inspire the chemists preparing them
Succinct, readable treatment of important concepts and applications geared towards advanced undergraduates and graduate students
Each synthesis covered begins with a brief discussion of the target molecule and challenges they present, followed by retrosynthetic considerations
Contents
Chapter 1 A Simple Holistic Approach to Planning a Synthesis
Chapter 2 Vying for Control: The Synthesis of Reserpine and Quinine
Chapter 3 A Helping Hand from Nature? Bioinspired Synthesis and Semi-synthesis
Chapter 4 Prostaglandins and Triquinanes: Fertile Ground for Method Development
Chapter 5 Polyketide Synthesis: The Challenge of Acyclic Stereocontrol
