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Full Description
Volume 25, entitled Modern Avenues in Metal-Nucleic Acid Chemistry, of the series Metal Ions in Life Sciences (MILS), provides a timely overview of selected relevant developments in a field which previously had a pronounced focus on fundamental chemistry aspects such as coordination principles, structural chemistry, and consequences for biological processes and disease-related medicinal issues. More recently, also as a consequence of the advent of supramolecular chemistry, advancements in nanochemistry, and new bio-analytical methods, novel aspects of this field have emerged. MILS-25 gives a state-of-the-art account on the present state of research in this field, addressing, among others, porous materials, non-covalent interactions, stimuli-responsive bioconjugates, DNA-templated metal arrays and nanoclusters, genotyping, guanine quadruplexes, and riboswitches. It consists of 15 comprehensive chapters with over 1600 citations, 160 figures (90 of them in color), with key contributions from 40 international experts from Europe, Asia, and America. It is an essential resource for scientists from numerous disciplines, ranging from materials science to biochemistry, by way of classical chemistry and physics.
It offers an update on nucleic acid - metal complex bioconjugates and their applications
It provides an insight into coordination polymers involving nucleic acid components
It covers a wide range of nucleic acids, from DNA duplexes, triplexes and quadruplexes to RNA
Contents
Chapter 1 Porous Materials Built Up From Metal-Nucleobase Materials
Garikoitz Beobide, Oscar Castillo, Antonio Luque, and Sonia Pérez-Yáñez
Chapter 2 Cytosine and Its Derivatives as Useful Tools to Build Unusual and Fascinating Architectures
Teresa F. Mastropietro and Giovanni De Munno
Chapter 3 Coordination Polymers with Nucleobase Derivatives: From Electronic Nanodevices to Sensors
Noelia Maldonado and Pilar Amo-Ochoa
Chapter 4 Heavy Coinage Metal Nucleobase, Nucleoside and (Oligo)Nucleotide Systems: Recent Developments in Self-assembly, Opto-electronics, and DNA Integration
Andrew Houlton
Chapter 5 Interplay between Noncovalent Interactions and Metal Ions in Nucleic Acids and Their Constituents
Miquel Barceló-Oliver, Antonio Frontera, Juan Jesús Fiol, Ángel García-Raso, and Ángel Terrón
Chapter 6 Biological Implications of Metal-Nucleobase Complexes
Saurabh Joshi, Ankita Jaiswal, Rajneesh Kumar Prajapati, and Sandeep Verma
Chapter 7 Stimuli-Responsive DNA-Binding Metal Complexes
Tim Kench and Ramon Vilar
Chapter 8 How Do Cationic Pt(II) Complexes Modify the Higher-Order Structure of DNA?
Seiji Komeda, Masako Uemura, Yuko Yoshikawa, and Kenichi Yoshikawa
Chapter 9 Metals in Genotyping: From SNPs to Sequencing
Tuomas Lönnberg
Chapter 10 Nucleic Acids for the Preparation and Control of Continuous Hybrid Metallic Assemblies
Miguel A. Galindo, Fátima Linares, Alicia Domínguez-Martín, and Antonio Pérez-Romero
Chapter 11 Recent Advances in the Development of Metal-Responsive Functional DNAs Based on Metal-Mediated Artificial Base Pairing
Yusuke Takezawa and Mitsuhiko Shionoya
Chapter 12 Nucleic Acid-Templated Metal Nanoclusters
Rweetuparna Guha and Stacy M. Copp
Chapter 13 G-Quadruplex Nucleic Acids and the Role of Metal Ions: Insights from Quantum Chemical Bonding Analyses
Celine Nieuwland and Célia Fonseca Guerra
Chapter 14 Transition Metal-Binding G-Quadruplex DNA
Lukas M. Stratmann and Guido H. Clever
Chapter 15 Metabolite Regulation by Riboswitches: The Role of Metal Ions in Folding, Ligand Binding, and Functionality
Maria Reichenbach, Sofia Gallo, and Roland K.O. Sigel
Index
