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Full Description
Gut microbiomes are dynamic communities varying from population to population and throughout life. In Western societies, a toxic metabolic shift of gut microbiomes is a driver and underestimated risk factor for the development of many noncommunicable chronic pathologies. This book identifies the root cause of these deleterious microbial changes. During the last several decades, increased consumption of animal products, coinciding and correlating with global climate change, has been a contributing cause of undesirable gut microbiome changes.
Key Features
Establishes a connection between poor gut microbiome health and chronic disease and cancer development
Demonstrates how animal products and low-fiber diet patterns induce a detrimental metabolic transition of the gut microbiome from a human health-maintaining towards a disease-promoting state
Discusses the opportunity of a toxic microbial metabolic signature as a powerful clinical and diagnostic tool to effectively predict chronic disease and cancer development
Provides the latest evidence on different strategies to rebuild a healthy microbiome metabolism and effectively prevent noncommunicable diseases and colorectal cancer
Documents the gut microbiome benefits of a plant-based diet
Contents
Table of Contents
Dedication
Preface
Introduction
Chapter 1: Diet related chronic diseases are the most critical health problem of modern societies - how did that happen?
Chapter 2: The "industrialized" microbiome - a caution label for a global epidemic
Missing microbes - does it matter?
Chapter 3: The subtle problems of microbiome research
Is the microbiome "oversold"?
Is microbiome science heading in the wrong direction?
Chapter 4: The gut microbiome: a new perspective
Our microbiome is a metabolic organ
Functional omes: metabolites over species
Finding a new definition for a "healthy" microbiome and "dysbiosis"
Chapter 5: Shaping the microbial behavior
Diet: the master educator of the gut microbiome
Starving the microbial self: a foundation for developing a chronic disease
Chapter 6: The toxic microbiome
"It's not the fiber, it's the animal protein"
Protein fermentation
Fat toxicity
Secondary bile acids
Heme iron
TMAO: the way to a man's heart is through his gut microbiota
Toxicomicrobiomics
A toxic microbiome: useful for predicting chronic diseases?
Chapter 7: How to build a healthy gut microbiome and prevent chronic diseases
The "true" human diet: are humans really omnivores?
"The Paleo diet is a myth"
Protein concerns: Do we get enough on plants?
Feeding microbes for disease prevention and treatment
Chapter 8: "Fixing" the microbiome - Can we restore a healthy microbiome by other means than diet?
Probiotics - hype or hope?
Fecal microbial transplantation or "The Power of Poop"
The "Wild West" of microbiome science: drugging the microbiome and personalized nutrition
Glossary
Abbreviations
Literature