Full Description
Gene delivery is a transport of genes of therapeutic values into the chromosomes of the cells or tissues which can be targeted to replace the faulty genes. In last two decades lot of research efforts are dedicated to gene delivery for therapeutic applications. Today gene therapy is promising approach in treatment of genetic diseases including mitochondrial related diseases like blindness, muscular dystrophy, cystic fibrosis, and some cancers.
Gene Delivery Systems: Nano Delivery Technologies observes the exploration of nanotechnology for gene therapy and gene delivery. Written by prominent authors in the field, this book covers various aspects of gene delivery including challenges in delivering gene therapy, advances in genome editing, RNA-based gene therapy, Green nanoparticles for oligonucleotide delivery.
Additional features include"
Provides the most up to date information on the development of gene therapy, from the technology involved to gene correction and genome editing.
Includes knowledge of the current application of CRISPR/Cas9 gene-editing technique; an approach that has recently been given the Noble Prize.
Examines the development of mRNA vaccines for Covid -19 in challenging pandemic scenario
Discusses siRNA, mRNA, and DNA plasmids.
Contents
Chapter 01
Challenges in delivering gene therapy
Chapter 02
Advances in genome editing: the technology of choice for precise and efficient disease treatment, with special focus on nano delivery systems
Chapter 03
Extracellular vesicles for nucleic acid delivery: progress and prospects for safe RNA-based gene therapy
Chapter 04
Green nanoparticles for oligonucleotide delivery
Chapter 05
Development of mRNA vaccines for Covid -19 in challenging Pandemic scenario
Chapter 06
Gene therapy for cardiovascular diseases: clinical evidences
Chapter 07
Current application of CRISPR/Cas9 gene-editing technique to eradication of HIV/AIDS
Chapter 08
siRNA delivery for therapeutic applications using nanoparticles
Chapter 09
Clinical perspectives on Gene therapy for retina and eye diseases
Chapter 10
Herpesvirus microRNAs for use in gene therapy immune-evasion strategies
Chapter 11
siRNA delivery for therapeutic applications using nanoparticles
Chapter 12
Gene therapy and small molecule treatment for cystic fibrosis
Chapter 13
CRISPR gene therapy recent trends and clinical applications
Chapter 14
Clinical applications of gene therapy for Immuno-deficiencies
Chapter 15
Regulatory challenges for nano gene delivery
