薬物動態学の基礎（第２版） Basic Pharmacokinetics （2ND）

Jambhekar, Sunil S./ Breen, Philip J.

Pharmaceutical Press（2012/03発売）

• 製本 Paperback:紙装版/ペーパーバック版
• 言語 ENG
• 商品コード 9780853699804
• DDC分類 615.7

基本説明

Addresses how the principles of pharmacokinetics and biopharmaceutics can be applied to successful drug therapy.

Full Description

Basic Pharmacokinetics provides an understanding of the principles of pharmacokinetics and biopharmaceutics and of how these principles can be applied to achieve successful drug therapy.

Contents

1. Introduction and Overview 2. Mathematical Review 3. Intravenous Bolus Administration 4. Clearance Concepts 5. Drug Absorption From the Gastrointestinal Tract 6. Extravascular Routes of Drug Administration 7. Bioavilability/bioequivalence 8. Factors Affecting Drug Absorption 9. Gastrointestinal Absorption 10. Continuous Intravenous Infusion 11. Multiple Dosing: Intravenous Bolus Administration 12. Multiple Dosing: Extravascular Routes of Drug Administration 13. Two-compartment Model 14. Multiple Intermittent Infusions 15. Non-linear Pharmacokinetics 16. Metabolite Pharmacokinetics 17. Drug Interactions 18. Pharmacokinetics and Pharmacodynamic Relationships 19. Pharmacokinetics and Pharmacodynamics of Biotechnology Drugs 20. Pharmacokinetic Data Fitting