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Full Description
Macrocyclic lactones are chemical compounds that represent the main treatment for parasitic diseases of animals, not only for helminth infections, but also a number of major ectoparasitic infestations.There has been no comprehensive book on this subject for more than a decade and this book fills this gap and provides detailed coverage of the basic science of these drugs and their mode of action, as well as their clinical use in farm and companion animals and in humans.
Contents
1: Chemistry, Pharmacology and Safety of the Macrocylic Lactones 2: Ivermectin, abamectin, eprinomectin, W L Shoop, Merck & Co., USA and M D Soll, Merial, USA 3: Doramectin, selamectin, G A Conder, Pfizer Central Research, USA and W J Baker, Pfizer Central Research, USA 4: Milbemycin oxime, M Jung, J Saito, G Buescher, M Maurer and J F Graff, Novartis Animal Health, Switzerland 5: Moxidectin, D W Rock, R Delay, and M Glidden, Fort Dodge Animal Health, Agricultural Research Center, USA 6: Pharmacokinetics of the Macrocyclic Lactones: Conventional Wisdom and New Paradigms, D R Hennessy, CSIRO Animal Production, Sydney, Australia and M R Alvinerie, INRA Laboratoire de Phamacologie, Toulouse, France 7: Mode of Action of the Macrocyclic Lactones, R J Martin, Iowa State University, USA and A P Robertson 8: Ecological Impact of Macrocyclic Lactones in Dung Fauna, J W Steel, CSIRO Animal Production, Sydney, Australia and K Wardaugh, CSIRO Entomology, Australia 9: Resistance against Macrocyclic Lactones, R Pritchard, McGill University, Canada 10: The Use of ML's to Control Parasites of Cattle 11: General, J Vercruysse and R Rew 12: Use of MLs to control cattle parasites in Europe, J Vercruysse and R Rew 13: Use of MLs to control cattle parasites in North America, R Rew and J Vercruysse 14: Use of MLs to control cattle parasites in South America, C Eddi, Argentina, A Nari, Rome, Italy and J Carancostogolo, Buenos Aires, Argentina 15: Use of MLs to control cattle parasites in Australia and New Zealand, P Holdsworth, Director Scientific & Regulatory Affairs, Avcare, Australia 16: The Use of MLs to Control Parasites of Sheep and Goats, R L Coop, Moredun Research Institute, Edinburgh, UK, I Barger, Armidale, Australia and F Jackson, Moredun Research Institute, Edinburgh, UK 17: The Use of MLs to Control Parasites of Horses, C Monahan and T Klei, Louisiana State University, USA 18: The Use of MLs to Control Parasites of Pigs, J Arends, S&J Farms Animal Health, USA and J Vercruysse 19: The Use of MLs in the Control and Prevention of Heartworm and Other Parasites in Dogs and Cats, J Guerrero, University of Pennsylvania, USA, C Genchi, Universita degli Studi di Milano, Italy and J W McCall, University of Georgia, USA 20: The Use of MLs to Control Parasites of Domesticated Wild Ruminants, S Marley, Merial, Duluth, USA and G A Conder, Pfizer Central Research, USA 21: The Use of MLs to Control Parasites of Exotic Pets, S E Little, University of Georgia, USA, C B Greenacre, University of Tennessee, USA and R Kaplan 22: The Use of MLs to Control Parasites of Humans, K R Brown, Philadelphia, USA n Macrocylic Lactones as Antiparasitic Agents in the Future,T Geary, Pharmacia & Upjohn Co, Michigan, USA
