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基本説明
Highlights recent developments regarding the pharmacokinetics and bioavailability and clinical outcomes and methodology.
Full Description
Phytochemicals: Mechanisms of Action is the latest volume in a highly regarded series that addresses the roles of phytochemicals in disease prevention and health promotion. The text, an ideal tool for scientists and researchers in the fields of functional foods and nutraceuticals, links diets rich in plant-derived compounds, such as fruit, vegetables and whole grains, with decreased risk of chronic degenerative diseases.
Chapters highlight recent developments in three areas that have not been covered sufficiently in previous references. The treatment of pharmacokinetics and bioavailability addresses how phytochemicals get into the body, what happens to them, and how they are metabolized. The book also addresses mechanisms of action, which explains how phytochemicals work at the cellular level, and clinical outcomes and methodology, which focuses on reasonable biomarkers, as well as current and future methods that demonstrate clinical efficacy.
Backed with five decades of compelling evidence, Phytochemicals: Mechanisms of Action is an essential resource for anyone interested in functional foods and nutraceuticals. Throughout the discussions, areas of research need are identified, thus benefiting researchers developing new areas of interest or young researchers just beginning their careers.
Contents
Absorption and metabolism of anthocyanins: potential health effects. Common features in the pathways of absorption and metabolism of flavonoids. Pharmacokinetics and Bioavailability of Green Tea Catechins. The importance of in vivo metabolism of polyphenols and their biological action Cancer prevention by phytochemicals, modulation of cell cycle. Cancer chemoprevention by phytochemicals including flavanoids and flavanoids through modulating signal transduction pathways. Gene regulatin by glucosinolate hydrolysis products from broccoli. Healthy foods vs. phytosterol fortified foods for the primary prevention of coronary artery disease. Vascular effects of resveratrol. Development of a mixture of dietary carotenoids as cancer chemopreventive agents: C57BL/6J mice as a useful animal model for efficacy studies with carotenoids. Chemoprevention of colon cancer by curcumin.
