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基本説明
Intended for chemists entering medicinal chemistry research who have no knowledge of pharmacology.
Full Description
"Pharmacology for Chemists, Second Edition" is aimed at industrial and academic organic chemists holding advanced degrees who are entering the field of medicinal chemistry, and who have had little or no education in or exposure to the biological sciences, especially physiology and pharmacology. The first portion of this book concentrates on biological/pharmacological principles and concepts, and the second portion demonstrates how these concepts and principles are
applicable to the medicinal chemists efforts, by describing some selected categories of drugs as examples. The book is not intended to be a textbook of pharmacology, but rather is intended to serve as a tool to prepare the reader for further study and more in depth reading.
Contents
I Chemical and Biological Bases of Pharmacology
1: Some General Concepts of Pharmacology
2: Pharmacokinetics
3: Drug Metabolism
4: Drug Receptors
5: Principles of Pharmacological Assays
II The Peripheral and Central Nervous Systems
6: Some Basic Concepts of the Anatomy and Physiology of the Nervous System
7: The Noradrenergic and Dopaminergic Nervous Systems
8: The Cholinergic System
9: The Central Nervous System I. Psychotropic Agents
10: The Central Nervous System II. Sedatives and Hypnotics
11: Analgesics I.
12: Analgesics II. Opioid Analgesics
13: General and Local Anesthetics
III Pharmacology of Some Peripheral Organ Systems
14: The Cardiovascular System I: Anatomy and Physiology, Hypertension, Hyperlipidemia/Atherosclerosis, and Myocardial Infarction
15: The Cardiovascular System II
16: The Cardiovascular System III: Congestive Heart Failure. Diuretics
17: Pharmacology of Some Histamine-Implicated Diseases: Allergy, Asthma, and Gastric Hypersecretion
Glossary of Terms
Subject Index
