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Full Description
The field of biomaterials has seen an exponential growth over the last few years leading to new strategies and frontiers in the biomedical arena. This growth has been catalyzed by the need to accelerate the discovery and translation of emerging technologies in a number of areas such as tissue engineering where the delivery of bioactive agents can help to treat, repair or restore function of damaged tissues. The emergence of these new biomaterial based technologies
has resulted from the convergence of principles from various disciplines such as materials
science, bioengineering, molecular biology, biochemistry and nanotechnology.
Motivations to improve health and lower long-term treatment costs to consumers and insurers has fueled continuous innovation towards developing novel polymeric compositions which can be used to manufacture medical devices with markedly lower risk of failure and adverse immune reactions. Polymers represent the most versatile class of biomaterials, being extensively applied in biomedical applications ranging from surgical and ocular devices, implants and supporting materials, drug delivery
systems and drug device combinations, biosensors and other diagnostic assays, to tissue adhesives and tissue engineered constructs. This versatility results from the fact that polymers can be prepared in different compositions with a wide variety of structures and appropriate physicochemical, interfacial
and biomimetic properties to meet specific end applications.
This book presents the latest findings of the leading researchers in the field of polymeric biomaterials. It consists of 13 chapters which provide examples and reviews of recent developments in the synthesis, characterization, and applications of polymeric biomaterials.
Contents
Preface ; 1. Review: Polymeric Scaffold Materials for Two-Dimensional and Three-Dimensional in Vitro Culture of Hepatocytes ; Amol V. Janorkar ; 2. Fabrication and Degradation of Nanofibers Based on Luminescent Boron Dye-PLGA Blends ; Richard A. Murray, Guoqing Zhang, Drew Harmata, Rebekah A. Neal, Edward A. Botchwey, and Cassandra L. Fraser ; 3. Polymer Gel Systems for Nerve Repair and Regeneration ; Shanfeng Wang and Lei Cai ; 4. Surface Patterning Using Self Assembled Monolayers (SAMs) ; Rahul Bhure and Anil Mahapatro ; 5. Advancing SPRi Measurements with Novel Biosensors for Studying Surface-Biomolecule Interactions ; Michael C. Weiger, Khaled Aamer, Joachim Kohn, and Matthew L. Becker ; 6. Development of ?-Carrageenan Poly(acrylic acid) Interpenetrating Network Hydrogel as Wound Dressing Patch ; Haydee Dalafu, Modesto T. Chua, and Soma Chakraborty ; 7. Absorbable Polyurethanes ; Rao S. Bezwada ; 8. Formation and Characterization of Chitosan-Based Coatings on Stainless Steel ; Gary Halada, Prashant Jha, Karl Nelson, Wei Zhao, Chad S. Korach, Aaron Neiman, So-Jeung Lee, and Eric Mintzer ; 9. Cyclic Dithiocarbonates: Novel in Situ Polymerizing Biomaterials for Medical Applications ; Ankur S. Kulshrestha, Walter R. Laredo, Tom Matalenas, and Kevin L. Cooper ; 10. Synthesis of Morpholine-2,5-dione Monomers for the Preparation of Polydepsipeptides ; Mena Abdelmelek, Mary Nguyen, Valerie Bradford, Brent Iverson, and Laura Suggs ; 11. Nitric Oxide and Drug Releasing Hydrolysable Macromers, Oligomers and Polymers ; Rao S. Bezwada ; 12. Metalloporphyrin based Biomimetic Catalysts for Materials Synthesis and Biosensing ; Subhalakshmi Nagarajan, Ferdinando F. Bruno, Lynne Samuelson, Jayant Kumar, and Ramaswamy Nagarajan ; 13. Design of Highly Functional Antiferritin-Immunolatex by Hybridization of Antiferritin/Mixed-PEG Polymers onto Polystyrene Submicroparticles ; Xiaofei Yuan, Dolca Fabregat, Keitaro Yoshimoto, and Yukio Nagasaki ; Indexes ; Author Index ; Subject Index
