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Full Description
Systems Biology is an interdisciplinary approach to the study of life made possible through the explosion of molecular data made available through the genome revolution and the simultaneous development of computational technologies that allow us to interpret these large data sets. Systems Biology has changed the way biological science views and studies life and has been implemented in research efforts across the biological sciences. Systems Biology and Livestock Science will be the first book to review the latest advances using this research methodology in efforts to improve the efficiency, health, and quality of livestock production. Systems Biology and Livestock Science opens with useful introductory chapters explaining key systems biology principles. The chapters then progress to look at specific advances in fields across livestock science. Coverage includes, but is not limited to, chapters on systems biology approaches to animal nutrition, reproduction, health and disease, and animal physiology.
Written by leading researchers in the field, Systems Biology and Livestock Science, will be an invaluable resource to researchers, professionals, and advance students working in this rapidly developing discipline.
Contents
List of Contributors vii
Preface xi
Chapter 1. Introduction to Systems Biology for Animal Scientists 1
Christopher K. Tuggle, Fadi Towfic, and Vasant G. Honavar
Chapter 2. Modeling Approaches in Systems Biology, Including Silicon Cell Models 31
Alexey N. Kolodkin, Fred C. Boogerd, Frank J. Bruggeman, and Hans V. Westerhoff
Chapter 3. The IUPS Physiome Project: A Worldwide Systems Biology Initiative 53
Gregory O'Grady, Peng Du, and Leo K. Cheng
Chapter 4. Systems Biology in Livestock Health and Disease 83
Gordon M. Kirby
Chapter 5. Systems Biology of Host-Food-Microbe Interactions in the Mammalian Gut 109
Vitor A.P. Martins dos Santos, Michael Muller, Willem M. de Vos, Jerry Wells, Marinus F.W. te Pas, Guido Hooiveld, Peter van Baarlen, Mari A. Smits, and Jaap Keijer
Chapter 6. From Visual Biological Models Toward Mathematical Models of the Biology of Complex Traits 137
Marinus F.W. te Pas, Arend J.W. Hoekman, and Ina Hulsegge
Chapter 7. Molecular Networks as Sensors and Drivers of Uterine Receptivity in Livestock 161
Stefan Bauersachs and Eckhard Wolf
Chapter 8. Modeling Approaches to Link Various Levels of Organization in Animal Physiology 191
Andre Bannink, James France, and Jan Dijkstra
Chapter 9. Systems Biology and Animal Nutrition: Insights from the Dairy Cow During Growth and the Lactation Cycle 215
Juan J. Loor, Massimo Bionaz, and Guido Invernizzi
Chapter 10. Host-Pathogen Interactions 247
Mari A. Smits and Dirkjan Schokker
Chapter 11. Systems Biology in Livestock Science and Commercial Livestock Business 277
Marinus F.W. te Pas, Henri Woelders, and Andre Bannink
Index 287
