Full Description
Medical Pharmacology & Therapeutics, now in its fifth edition, offers medical students all they need to know to become safe and effective prescribers. It forms a complete, integrated resource for basic pharmaceutical science, pathophysiology, clinical pharmacology, and therapeutics.The fifth edition has been extensively revised and updated throughout. Key features include:Clear, disease-based approach.Presentation of how drugs are used in clinical practice.Succinct explanations of the major pathogenic mechanisms of each disease and consequent clinical signs and symptoms.Comprehensive reviews of major drug classes relevant to each disease.Structured approach to the principles of disease management - outlining core principles of drug choice and planning a therapeutic regimen for common diseases.Quick-reference drug compendia illustrating key similarities and differences among all BNF-listed drugs in each class.Comes with free e-book on StudentConsult.New sections on key and evolving topics, including prescribing safety and pharmacovigilance.Updated figures to further clarify complex areas.Over 800 revised multiple-choice and case-based questions for self-assessment.
Contents
SECTION 1 General principles1. Principles of pharmacology and mechanisms of drug action 2. Pharmacokinetics 3. Drug discovery, safety and efficacy 4. The nervous system, neurotransmission and the peripheral autonomic nervous system SECTION 2 The cardiovascular system5. Ischaemic heart disease 6. Systemic and pulmonary hypertension 7. Heart failure 8. Cardiac arrhythmias 9. Cerebrovascular disease and dementia 10. Peripheral vascular disease 11. Haemostasis SECTION 3 The respiratory system12. Asthma and chronic obstructive pulmonary disease 13. Respiratory disorders: cough, respiratory stimulants, cystic fibrosis and neonatal respiratory distress syndrome SECTION 4 The renal system14. Diuretics 15. Disorders of micturition 16. Erectile dysfunction SECTION 5 The nervous system17. General anaesthetics 18. Local anaesthetics 19. Opioid analgesics and the management of pain 20. Anxiolytics, sedatives and hypnotics 21. The major psychotic disorders: schizophrenia and mania 22. Depression, attention deficit hyperactivity disorder and narcolepsy 23. Epilepsy 24. Extrapyramidal movement disorders and spasticity 25. Other neurological disorders: multiple sclerosis, motor neuron disease and Guillain-Barre syndrome 26. Migraine SECTION 6 The musculoskeletal system27. The neuromuscular junction and neuromuscular blockade 28. Myasthenia gravis 29. Non-steroidal anti-inflammatory drugs 30. Rheumatoid arthritis, other inflammatory arthritides and osteoarthritis 31. Hyperuricaemia and gout SECTION 7 The gastrointestinal system32. Nausea and vomiting 33. Dyspepsia and peptic ulcer disease 34. Inflammatory bowel disease 35. Constipation, diarrhoea and irritable bowel syndrome 36. Liver disease 37. Obesity SECTION 8 The immune system38. The immune response and immunosuppressant drugs 39. Antihistamines and allergic disease SECTION 9 The endocrine system and metabolism40. Diabetes mellitus 41. The thyroid and control of metabolic rate 42. Calcium metabolism and metabolic bone disease 43. Pituitary and hypothalamic hormones 44. Corticosteroids (glucocorticoids and mineralocorticoids) 45. Female reproduction 46. Androgens and anabolic steroids 47. Anaemia and haematopoietic colony-stimulating factors 48. Lipid disorders SECTION 10 The skin and eyes49. Skin disorders 50. The eye SECTION 11 Chemotherapy51. Chemotherapy of infections 52. Chemotherapy of malignancy SECTION 12 General features: toxicity and prescribing53. Drug toxicity and overdose 54. Substance abuse and dependence 55. Prescribing, adherence and information about medicines 56. Drug therapy in special situations Index
